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SmartyPance:Endocrine > Pituitiary Gland - Sheet1 > Flashcards

Pituitiary Gland - Sheet1 Flashcards

1
Q

Decreased growth hormone from infancy results in which condition?

A

Dwarfism

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2
Q

Frontal bossing, tall stature and macroglossia represent which disorder?

A

Acromegaly

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3
Q

What is the most common cause of acromegaly?

A

Pituitary adenoma

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4
Q

A patient has polyuria, polydipsia and nocturia. Blood glucose and HbA1c are both normal. What labs should be checked to further investigate?

A

Serum sodium and osmolality (increased in diabetes insipidus) - Urine osmolality(decreased in diabetes insipidus)

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5
Q

Will desmopressin (an ADH analog) successfully treat nephrogenic diabetes insipidus?

A

No - The kidneys are resistant to ADH in nephrogenic diabetes insipidus

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6
Q

What lab value can assist in distinguishing hypernatremia from dehydration versus hypernatremia due to diabetes insipidus?

A

Urine osmolality - Diabetes insipidus: urine osmolality will be low - Dehydration: urine osmolality will be high

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7
Q

A 42 year old male presents with galactorrhea and visual changes which consist of temporal field loss. What imaging is appropriate?

A

MRI to look for pituitary adenoma

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8
Q

What is the specific type of procedure used to surgically treat acromegaly from a pituitary adenoma?

A

Trans-sphenoidal resection of pituitary

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9
Q

What is the cause of 95% of acromegaly?

A

Pituitary adenoma

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10
Q

A 21 year old male who is 6’8”, has acral enlargement and a BP of 160/95 mmHg presents. What imaging study would be appropriate as part of your work up?

A

MRI for pituitary adenoma

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11
Q

How will height be affected in an patient who develops acromegaly in adulthood?

A

Height does not change if the acromegaly develops after the growth plates have closed

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12
Q

How does the decreased growth hormone in pituitary dwarfism affect the growth plates?

A

Growth plates fibrose early but close later in children with pituitary dwarfism

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13
Q

Is central or nephrogenic diabetes insipidus more likely to respond to desmopressin?

A

Central (Nephrogenic is resistant to ADH and desmopressin is an ADH analog)

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14
Q

What endocrine disorder can Tolvaptan cause?

A

Nephrogenic diabetes insipidus

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15
Q

What do bitemporal hemianopsia and galactorrhea suggest?

A

Pituitary tumor

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16
Q

What disorder is most likely with Polydipsia, polyuria, increased serum osmolality and decreased Urine osmolality?

A

Diabetes insipidus

17
Q

Treatment of choice for central diabetes insipidus (DI) and DI associated with pregnancy?

A

Desmopressin

SmartyPance:Endocrine (7 decks)

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