Pituitary Gland Flashcards

1
Q

Where does the pituitary gland located?

A

Sella turcica or Turkish saddle (small cavity in the sphenoid bone of the skull)

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2
Q

Pituitary gland and hypothalamus is connected by

A

Infundibular stalk

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3
Q

True or False: All pituitary hormones have circadian rhythm

A

True

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4
Q

Pituitqry gland is also known as

A

Hypophysis

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5
Q

What are the region of the hypophysis

A

Adenohypophysis and Neurohypophysis

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6
Q

It is the true endocrine gland

A

Anterior pituitary (adenohypophysis)

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7
Q

It is the true endocrine gland

A

Anterior pituitary (adenohypophysis)

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8
Q

What hormones does the adenohypophysis regulate and produce

A

FSH, LH, ACTH, GH, TSH, Prolactin (FLAGToP)

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9
Q

Types of Cells in the Adenohypophysis by Immunochemical test

A

Somatotrophs - GH
Lactotrophs - Prolactin
Tyrotrophs - TSH
Gonadotrophs - LH and FSH
Corticotrophs - POMC (proopiomelanocortin)

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10
Q

It is the most abundant of all pituitary hormones

A

GH

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11
Q

GH is controlled by

A

GH-RH and Somatostatin

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12
Q

Anabolic and metabolic actions of GH are facilitated by

A

Somatomedin C

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13
Q

The structure of GH is similar to

A

Prolactin and human placental lactogen

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14
Q

The metabolic effect of GH

A

Metabolize fat stores while conserving glucose

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15
Q

Major stimulus of GH

A

Deep sleep (markedly increase GH)

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16
Q

Major inhibitor of GH

A

Somatostatin

17
Q

Physiologic stimuli of GH (increased GH)

A

Stress, fasting, high-protein diet

18
Q

Pharmacologic stimuli of GH (increased GH)

A

Sex steroids, apomorphine, and levodopa

19
Q

GH suppressors

A

Glococorticoids and elevated fatty acid

20
Q

Significant in increased GH (disorders)

A

Acromegaly, chronic malnutrition, renal disease, cirrhosis, sepsis, DM

21
Q

Significant in decreased GH (disorders)

A

GHD, obesity, hypothyroidism

22
Q

Common method for GH

A

Chemiluminescent Immunoassay

23
Q

Reference value of GH (fasting)

A

<10 ng/mL

24
Q

it is the most commn cause of of GH deficiency in childrenq

A

Idiopathoc GH