Pineal Gland Flashcards
Pineal gland is attached to
Midbrain
What does pineal gland secretes and function?
Melatonin. Decreases the pigmentation of the skin
Possible cause of disfunction of pineal gland
Accidental and developmental conditions (pineal tumors, craniopharyngiomas, and injuries to the gland)
Melatonin is also called
N-acetyl-5-hydroxytryptamine
The secretions of pineal gland is controlled by
Nerve stimuli
Melatonin is secreted only during
Dark period of the day. Night
Melatonin is a marker of
Phase internal circadian clock (regulate the circadian system and sleep pattern)
Plasma melatonin in adults
60-70 pg/mL when measured with high specificity assay
Concentration of melatonin in saliva
3x lower than in plasma
It is a good marker of melatonin secretion in urine
6-sulfatoxylmelatonin
Method of choice for melatonin
Immunoassay
Health benefits from melatonin
Anti-oxidat and anti-aging properties
Potent free radical scavengers
More effective than glutathione in reducing oxidative stress
Factors that influence melatonin plasma level
False increased: posture (night), exercise, caffeine
False decreased: alcohol, and aspirin