Pineal Gland Flashcards

1
Q

Pineal gland is attached to

A

Midbrain

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2
Q

What does pineal gland secretes and function?

A

Melatonin. Decreases the pigmentation of the skin

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3
Q

Possible cause of disfunction of pineal gland

A

Accidental and developmental conditions (pineal tumors, craniopharyngiomas, and injuries to the gland)

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4
Q

Melatonin is also called

A

N-acetyl-5-hydroxytryptamine

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5
Q

The secretions of pineal gland is controlled by

A

Nerve stimuli

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6
Q

Melatonin is secreted only during

A

Dark period of the day. Night

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7
Q

Melatonin is a marker of

A

Phase internal circadian clock (regulate the circadian system and sleep pattern)

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8
Q

Plasma melatonin in adults

A

60-70 pg/mL when measured with high specificity assay

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9
Q

Concentration of melatonin in saliva

A

3x lower than in plasma

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10
Q

It is a good marker of melatonin secretion in urine

A

6-sulfatoxylmelatonin

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11
Q

Method of choice for melatonin

A

Immunoassay

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12
Q

Health benefits from melatonin

A

Anti-oxidat and anti-aging properties
Potent free radical scavengers
More effective than glutathione in reducing oxidative stress

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13
Q

Factors that influence melatonin plasma level

A

False increased: posture (night), exercise, caffeine
False decreased: alcohol, and aspirin

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