Pituitary gland Flashcards

1
Q

how does negative feedback work

A

as a hormone increases in conc it inhibits the release of another hormone

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2
Q

how many hormones does the anterior pituitary gland release

A

7

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3
Q

what are the 7 hormones the anterior pituitary release

A
FSH
LH
ACTH
GH
TSH
Prolactin
Melanocyte stimulating hormone
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4
Q

what hormones does the posterior pituitary release

A

ADH

OXYTOCIN

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5
Q

blood supply to the anterior pituitary

A

none

receives blood supply through a portal venous system from hypothalamus

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6
Q

what is the hypothalamus

A

collection of brain nuclei
connects to almost all other areas of brain
important for homesotasis

control of endocrine function via pituitary

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7
Q

what hormones does the hypothalamus release

A

thyrotropin releasing hormone TRH
corticotropin releasing hormone CRH
gondatropin releasing hormone

dopamine

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8
Q

when is GH released

A

by low glucose
exercise
sleep

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9
Q

action of growth hormone

A

linear growth in children
acquisition of hormone
stimulates protein synthesis . lipolysis
psychological well being

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10
Q

what is prolactin used for

A

stimulates the production of breast milk

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11
Q

what is the HPA axis for

A

in response to stress hypothalamic pituitary axis

to release cortisol

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12
Q

how does the HPA AXIS WORK

A

Hypothalamus releases CRH-
Causes the ant pituitary to release ACTH to act on adrenal gland
adrenal releases cortisol from zona fasiculata
too much cortisol inhibits acth thus allowing for negative feedback

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13
Q

what is crh

A

corticotropin releasing hormone

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14
Q

what is acth

A

adrenocorticotropic hormone

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15
Q

what is the HPS or Insulin growth factor for

A

regulates the growth and development of childrn

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16
Q

how does the HPS axis work

A

hypothalamus releases GHRH +ve and somastatin -ve
causes ant pituitary to release GH
GH acts on the liver to make insulin like growth factor

17
Q

what does insulin like growth factor promote

A

skeletal growth and bone
density
muscle strength
protein synthesis

18
Q

Which of the anterior and posterior pituitary produces its own hormones

A

The anterior pituitary produces and releases its own hormones, under the regulation of hormones made by the hypothalamus

19
Q

Which layer of the adrenal cortex is responsible for the secretion of cortisol?

A

zona fasiculata

20
Q

how does the hpg axis work in men

A

Hypothalamus releases gnrh
Causes ant pituitary to release FSH and lh
Causes the testes to release testosterone

Negative :
When conc of testosterone in blood is too high then the test inhibits the release of gnrh from hypothalamus and lh ans fsh from ant pituitary

21
Q

what does hpg axis mean

A

hypothalamic pituitary gonadatropin releasing hormone axis

22
Q

what does LH in men do

A

stimulates leydig cells which causes the testes to release testosterone

23
Q

how does the HPP axis work

A

hypothalamus releases TRH in response to baby suckling on boob
this causes ant pit to releases prolactin which causes lactation
too much prolactin in blood then dopamine is released to inhibit prolactin

24
Q

where is oxytocin synthesised

A

hypothalamus- paraventricular nucleus

25
Q

Function of oxytocin

A

Acts on breast milk to allow milk to move through laciferous ducts to be expressed through the nipple
On the uterus causing uterine contractions

26
Q

Where is ADH SYNTHESISED

A

supraoptic nucleus in the hypothalamus