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Endocrinology > Pituitary Disorders > Flashcards

Pituitary Disorders Flashcards

1
Q

What are some potential causes of pituitary hyperplasia?

A

Pregnancy
Long standing hypothyroidism
Long-standing primary hypogonadism

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2
Q

What is the best study for stellar masses or pituitary tumors?

A

MRI w/ Gadolinium

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3
Q

What are some potential causes of Stellar Masses?

A 
Metastatic Dz
Tumors
Cysts
Abscesses
Lymphocytic hypophysitis
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4
Q

What is the most common type of pituitary tumor?

What are their S/Sx?

A

Hyperprolactinemia

oligomenorrhea, AMENORRHEA, GALACTORRHEA (milk discharge from the nipples)

Infertility

Decreased libido

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5
Q

What inhibits prolactin release?

A

Dopamine

GnRH –> Dopamine –> Prolactin

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6
Q

What are some potential causes of Hyperprolactinemia?

Why is this happening / explain this from a pathophysiologic / hormone level?

What would the Tx be?

A 
Pregnancy
Hypothalamic Dz (tumors)
Pituitary stalk trauma 
Adenoma w/ ICP "pressure effect"
Drug use (antipsychotics, estrogen, verapamil)
Hypothyroidism
CRF 
Chest wall injury

Causes decrease in FSH and GnRH which controls dopamine (which is essential to inhibit prolactin)

Dopamine Agonist
Bromocriptine
Cabergoline

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Endocrinology (14 decks)

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