Pituitary disease

Question 1

tests to order for amenorrhea

Answer 1

• B HCG
• prolactin
• sTSH
• FSH
• LH
• Estradiol

Question 2

Secondary causes of high prolactin

Answer 2

• pregnancy
• primary hypothyroidism
• drugs: antipsychotics, GI motility drugs-
• renal and liver failure

Question 3

Triple bolus stimulation test

Answer 3

GnRH
TRH
Insulin - to stimulate growth hormone and cortisol

Question 4

2 drugs that can cause hyper function prolactinoma

Answer 4

respiradone

Metaclopramide

Question 5

what are other causes of elevated growth hormone

Answer 5

Almost always pituitary adenoma

Question 6

Function of insulin in the stimulation test

Answer 6

Insulin will lower glucose levels, increase growth hormone - should increase glucose -

Question 7

Microadenoma is

Answer 7

a radiological term, describes a pituitary adenoma < 1cm

Question 8

> 1cm adenoma

Answer 8

macroademona

Question 9

how many individuals are affected by a pituitary adenoma

Answer 9

1 in 5 individuals

Question 10

2 dopamine agonists to treat prolactinomas

Answer 10

cabergoline

bromocriptine (more safety known in pregnancy)

Question 11

if dopamine treatment fails consider

Answer 11

more aggressive pituitary tumour subtype