pineal region tumors

Question 1

what are germ cells tumors of pineal region

Answer 1

germinomas, embryolnal carcinoma, endodermal sinus tumors (yolk sack tumors), and teratomas

Question 2

which germ cell tumors are malignant

Answer 2

all non germinomatous germ cell tumors excepts mature teratomas

Question 3

germ cells typically found

Answer 3

around puberty possibel in response to hoemones

Question 4

typical genetics in germ cells tumors

Answer 4

gain of 12 p and X chromosome

Question 5

which pineal germ tumors occur earlier

Answer 5

choriocarcinomas- 25% before age 9

Question 6

age group for pneoblasoma

Answer 6

infancy and childhood- pineocytoms older children/young adults

Question 7

which tumor produces AFP

Answer 7

yolk sac tumor ( endodermal sinus tumor)- less so embyonal carcinoma and immature teratoma

Question 8

what produces B-HCG

Answer 8

choriocarcinoma, mild with germinoma and embyonal carcinoma

Question 9

what is PLAP specific for

Answer 9

germinoma-