development Flashcards

1
Q

how long is the pregasrulation stage

A

post ovulatory 3 weeks

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2
Q

what are the three layers of ttissue formed by gastrulation

A

ectoderm
mesoderm
endoderm

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3
Q

what is the organizer for gastrulation

A

primative streak

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4
Q

what forms the notocord

A

epiblasts that surround hensen’s node- forms the notocord

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5
Q

what are notable defects of gasrulation

A

split cord malformations (SCM 1 (bony devision) and SCM 2 (
neuroenteric cyst
epidermoid cyst
dysraphyic malformations

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6
Q

what are the four steps of neurulation

A

Neuroal Plate formation
Neural plate midline bending
neural plate lateral wall bending
neuroal fold fusion

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7
Q

what may drive early brain enlargment

A

closure of the cranial neural tune which elarges the ventrular system and may drive brain growth

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8
Q

when do the neuropores close

A

24 days for anterior and 26 days for the caudal

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9
Q

defects of primary neuraltion

A

anencephaly
craniorachisis
myelomengioceal
myelochisis

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10
Q

what stage do dermoid cysts form

A

non dysjunction during neural tube closure

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11
Q

timing of secondary neurolation

A

POD 225 to 27 from the caudally from the posterior neuropore- process called cavitation

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12
Q

defects of secondary neural tube

A

filum terminale
terminal lipoma
myelocystocele
vater (vertebral anomonies, imperferate anus, trachealesophogeal fistula, and renal anomolies

OEIS- omphalocele, cloacal exstrophy, imperferate anus, and spinal anomolie)

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13
Q

when does lipomylomengiocele occur

A

likely primary neurolation or possibly premature dysjunction

faulure of caudal neural tumbe to migrate

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14
Q

what is associated with caudal agensiss

A

secondart neural tube development

lipomas of filum terminale

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15
Q

what causes caudal agensis

A

improper migrate of cells from primitive streak (gastrulation)

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16
Q

what does the verterbral bodies developfrom

A

proximal mesynchye ( somites)

17
Q

what leads to creation of encephaloceal

A

postneuralation- imparment of chrondrocranial growth from impaired mesenchym allows for herniation