Phytonutrients to Improve Detoxification Flashcards
Identify three phytonutrients that provide cellular protection against xenobiotic chemicals and toxic metals
Lutein: Eye
Carotenoids: Skin
Proanthocyanidins: Brain
Phytochelators definition
upregulators of metallothionein
soup for detox of heavy metals
corriander
What are metallothioneins
- Proteins composed of about 30% cysteine
- In absence of heavy metals, primary role is to transport Zn and Cu
- Known to efficiently bind several toxic metals (particularly Cd and Hg) and act as transporter of toxic metals to the liver or kidneys for conjugation and excretion
- Prevents reaction of toxic metals with other biomolecules, thus attenuating their toxicity
- Inducible
ZINC
Breast Cancer
CHEMOPREVENTIVE PHYTONUTRIENTS
• Green Tea/EGCG • Polyphenol-Rich Diet - quercetin -luteolin -resveratro -curcuminoids • Mediterranean-type diet • Organosulfur compounds - Cruciferous vegetables, garlic
Non-Phyto: 2/4/16-OH-E Ratios, Regular Exercise
Colon Cancer
CHEMOPREVENTIVE PHYTONUTRIENTS
- Polyphenols
- Berries
- Green tea/EGCG
- Flavonol from F&V-rich Diet, focus on isorhamnetin, kaempferol, myricetin, and quercetin
- Curcumin, pomegranate (preclinical evidence)
Increase F&V/Fiber/Exercise, Reduce red meat/alcohol/tobacco
Prostate CA
CHEMOPREVENTIVE PHYTONUTRIENTS
- Polyphenols
- Lycopene
- Pomegranate Juice
- Lignans (flax)
- Sulforaphane
Nutrients for Healthy Bile Flow
Vitamin C Vit B6 folic acid Vit B12 Mag choline inositol taurine methoinine betaine HCL • Artichoke leaf extract and other bitters
Two foods highest in flavonids
Cacao beans
elderberry
algae that decreases dioxin
chlorella
binds to aflotoxins
chlorophyllin
vitamin that helps with EMF
Vit D
phytochemicals for removing radiation
vit D
taurine
royal jelly
ginger
Avacado detox effect
MUFA) decreased IL6 increase with buger
flavones detox effect
bind to GABA - anxiolytic