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ENDOCRINO > Physiology thyroid gland > Flashcards

Physiology thyroid gland Flashcards

1
Q

Cutting what can cause aphony

A

Non-recurrent laryngeal nerve

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2
Q

Cutting the vagus nerve causes

A

Respiratory problems

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3
Q

What is used to detect nodules

A

Thyroid ecography

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4
Q

% of people having a 5th thyroid gland

A

10%

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5
Q

% of T4 undergoing deoiodination to T3

A

90%

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6
Q

Inhibition of TSH

A

Dopamine
Somatostatin
Glucocorticoids

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7
Q

Histology: what is provided by capillaries

A

iodide

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8
Q

Home to thyroid hormone production

A

Colloid

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9
Q

Main secondary receptor

A

cAMP

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10
Q

Ab binding to same receptor as TSH causing hyper activity DISEASE

A

Grave’s disease

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11
Q

Symtransporter getting iodide from circulation to gland

A

DIS

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12
Q

Iodide to colloid through which transporter

A

PENDRINE

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13
Q

Iodination occurs through which enzyme

A

TPO

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14
Q

Oxidation will give rise to

A

MIT and DIT

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15
Q

T3 composition

A

MIT + DIT

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16
Q

T4 composition

A

DIT + DIT

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17
Q

% T4 and T3

A

93% T4

7% T3

18
Q

Iodination and coupling done through which enzyme

A

TPO

19
Q

What allows release of T3 and T4 into circulatory system

A

Degradation of colloid droplets through lysosomes

20
Q

Which are recycled

A

Iodide and tyrosine

21
Q

Chaikoff effect

A

Radioactive I- released during nuclear attacks

Intake of iodide tablets to saturate I- necessity for the body to not absorb the radioactive I-

22
Q

Other use of iodide tablets

A

Treating hyperthyroidism

23
Q

% thyroid hormone bound and unbound

A

99% bound

1% not bound

24
Q

70% of thyroid hormone is bound to

A

TBG

25
Q

15-20% of thyroid hormone bound to

A

Albumin

26
Q

10-15% of thyroid hormone bound to

A

Transthyretin

27
Q

Production of T4 in

A

Thyroid gland

28
Q

T3 produced in

A

Periphery tissues

29
Q

% of T3 produced from T4

A

75%

30
Q

Half life of T3 and T4

A

T3 - 1 day

T4 - 6.2 days

31
Q

Conversion of T4 into T3 through enzyme

A

Deiodinase (D)

32
Q

Deosinases functioning in peripheral circulation

A

D1 and D2

33
Q

Deodinase functioning in hypothalamus and pituitary

A

D2

34
Q

Deosinase turning T4 into RT3 (inactive)

A

D3

35
Q

When is the conversion into RT3 important

A

In situations of stress

36
Q

Thyroid hormone and catechlamine are anabolic or catabolic

A

Catabolic

37
Q

When will the body inhibit catabolic action

A

When in disease

38
Q

Cathecolamine function

A

Prepare the body for exercise, increase HR

39
Q

TBG enter cells through

A

Diffusion

40
Q

T3 and T4 effect

A

Stimulate B adrenergic receptors –> production of cathecolamines

ENDOCRINO (4 decks)

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