Physiology Of Olfaction

Question 1

Location of the receptors of the olfactory sensory neurons

Answer 1

In the upper nasal Concha

Question 2

Stimulation of the sensory olfactory Receptors

Answer 2

Gaseous odorant particles bind to
G-protein coupled receptors on
dendrites of olfactory sensory
neurons
• This binding stimulates cAMP or
IP3 production and opens ionic
channels
• Influx of both Na+ and Ca++ with
efflux of Cl- causes depolarisation
of the olfactory neurons followed
by action potential travelling in
their olfactory nerve axons

Question 3

Whatbis the first order neuron in olfaction

Answer 3

Olfactory sensory neurons

Question 4

What is the 2nd order neuron in olfaction

Answer 4

Mitral and tuft cells

Question 5

Synapse between 1st and 2nd order neurons of olfaction occurs in…..

Answer 5

The Glomeruli

Question 6

Where does the lateral olfactory tract rely its neurons?

Answer 6

Temporal lobe of the same side

Question 7

Where does the medial olfactory tract rely its neurons?

Answer 7

Contralateral olfactory tract and limbic structures

Question 8

Where does the olfactory tract rely its neurons

Answer 8

Dorsomedial nucleus of
Thalamus, hypothalamus,
epithalamus, reticular
Formation

Question 9

What are the six primary olfactory areas

Answer 9

➢anterior olfactory nucleus
➢olfactory tubercle
➢piriform cortex
➢anterior cortical amygdaloid
nucleus
➢ periamygdaloid cortex
➢lateral entorhinal cortex