Physiology of menstrual cycle Flashcards

1
Q

How long is the follicular phase?

How long is the luteal phase?

A

14 days

14 days

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2
Q

FSH induces which cells to release more oestrogen?

A

Granulosa cells

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3
Q

What is oestrogen responsible for in reproductive system?

A

Secondary female characteristics

Develop breast tissue, vulva, vagina, uterus

Stimulate blood vessels in uterus and endometrium development

Thin cervical mucus - allowing sperm passage

Negative feedback on GnRH, FSH, LH

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4
Q

Which hormone’s rise causes ovulation?

A

LH

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5
Q

What does corpus luteum secrete?

A

Progesterone (most)

Oestrogen

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6
Q

Which day does ovulation occur

A

Usually 14th day in menstrual cycle

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7
Q

What is progesterone responsible for in reproductive system?

A

Released by corpus luteum after ovulation, released by placenta from 5-10 weeks.

Thicken and maintain endometrium

Thicken cervical mucus

Rise in body temperature

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8
Q

If the egg is fertilised, what hormone is released (from syncytiotrophoblast of embryo) that maintains the corpus luteum?

A

HCG

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9
Q

Corpus luteum breaks down, leading to reduction in which hormones and increase in which hormone?

A

Increase in FSH

Decrease in progesterone/oestrogen (menses)

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10
Q

Decrease in progesterone/oestrogen leads to what?

A

Break down of endometrium - menstruation

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11
Q

Which day does menstruation start of the menstrual cycle?

A

Day 1

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12
Q

Which layers are involved in the menses of menstruation?

A

Superficial and middle layers of the endometrium separate from the basal layer

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13
Q

How long does menstruation last?

A

1 - 8 days

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14
Q

When does LH spike happen?

A

Around 14 days

Just prior to ovulation (induces egg release from ovum)

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15
Q

What are the four stages of follicle development in the ovaries?

A

Primordial follicles
Primary follicles
Secondary follicles
Graafian follicles (antral)

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16
Q

At which stage of follicle development do the follicles develop FSH receptors?

A

Secondary follicle stage

Further development requires FSH, that’s why

17
Q

What hormone hjas a negative feedback on GnRh, LH/FSH?

A

Oestrogen

18
Q

______ cells of the endometrium release _________ that allow endometrium breakdown and uterus contraction in the menstrual cycle.

A

Stromal cells

Prostaglandin