Physiology Of Defecation Flashcards

1
Q

Functions of the colon

A

Absorption of water and electrolytes (osmosis)
Excretion of waste (motility)
Production of vitamins/regulation of immune system (microbiome)

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2
Q

Normal colonic transit time

A

24-48 hours

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3
Q

Length of colon in an adult

A

1.5m

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4
Q

What controls passage of stool into caecum from ileum

A

Ileocaecal valve

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5
Q

Parts of colon

A

Caecum
Ascending colon
Transverse colon
Descending colon
Sigmoid colon

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6
Q

What is the name of the bend between ascending and transverse colon

A

Hepatic flexure

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7
Q

Where does majority of absorption of water and electrolytes occur

A

Ascending colon
First part of transverse colon

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8
Q

What is the name of the bend between transverse and descending colon

A

Splenic flexure

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9
Q

Layers of the colonic wall

A

Mucosa
Muscularis mucosae
Submucosa
Muscularis propria
Subserosa
Serosa

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10
Q

histology of colonic mucosa

A

Single layer of columnar epithelium
Goblet cells
Lamina propria- inflammatory cells

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11
Q

Muscularis propria of colon

A

Inner circular muscle (CM)
Auerbach nerve plexus
Longitudinal muscle (LM)

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12
Q

Function of longitudinal muscle in colon muscularis propria

A

Segmental motility

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13
Q

Function of inner circular muscle in colon muscularis propria

A

Mass movement by peristalsis

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14
Q

Which nerve plexus is in the muscularis propria of the colon

A

Auerbach nerve plexus

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15
Q

Haustra

A

saccules in the colon that give it its segmented appearance. Haustral contraction is activated by the presence of chyme and serves to move food slowly to the next haustra, along with mixing the chyme to help with water absorption

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16
Q

Taenia coli

A

three bands of longitudinal smooth muscle on the colon surface

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17
Q

What produces Haustra

A

Longitudinal muscle

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18
Q

Nerve supply to colon

A

Enteric nervous system
Intrinsic
Extrinsic

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19
Q

What are receptors in colon (entry of faeces)

A

Mucosal stretch receptors

20
Q

Extrinsic nervous system

A

Parasympathetic
Sympathetic

21
Q

Intrinsic nervous system of colon

A

Myenteric plexus
Submucosal plexus

22
Q

Which nerve controls defecation

A

Pelvic nerve

23
Q

What stimulates defecation reflex

A

Parasympathetic stimulation

24
Q

Parts of anal sphincter

A

Internal hemorrhoid tissue
Levator ani muscle
Internal anal sphincter
External anal sphincter
External hemorrhoid tissue

25
Pudendal nerve
Somatic Controls external anal sphincter to maintain continence
26
4 phases of defecation
Basal Pre-expulsive Expulsive Termination
27
External anal sphincter
Circular striated muscle
28
Internal anal sphincter
Smooth muscle
29
Levator ani muscle
Support anal-rectum Part of pelvic floor
30
Puborectalis muscle
When contracted promotes continence 90 degree angle- bending analysis pathway
31
Basal phase of defecation
Colon- segmental contractions (mixing) Rectum - motor complexes (to keep rectum empty) Anal sphincter- tonic contraction Puborectalis- contracted (90 degree anorectal angle)
32
Anorectal angle to maintain continence
90 degrees
33
Pre-expulsive phase of defecation
Colon- high amplitude propagating contractions -mass movement of stool 8 times a day -gastro-colic reflex Rectum- fills causing distension -rectal compliance Anal sphincter- EAS maintains contraction -reflex relaxation of IAS (RAIR)- for stool sampling Puborectalis- remains contracted
34
Mass movement of stool per day
8 times
35
Stool sampling
Reflex relaxation of internal anal sphincter External anal sphincter maintains contraction Tests whether stool is solid, liquid, gas
36
Constipation
Condition where go to toilet less than 3 times a week
37
Expulsive phase of defecation
Rectum contracts IAS, EAS and PR relaxes Valsalva manoeuvre/posture aid emptying
38
Sitting posture while defecating
Puborectalis muscles chokes rectum to maintain continence
39
Squatting posture when defecating
Puborectalis muscle relaxes and straightens pathway to anus
40
Termination phase of defecation
Traction loss causes sudden contraction of EAS ( closing reflex) Valsalva ceases Change in posture to standing
41
Disorders of defecation - constipation/obstructive defecation
Consistency of stool Bowel motility Physical blockage to the bowel Pelvic floor disorders
42
Diagnostic testing for constipation/obstructive defecation
Colonic transit study Defecating proctogram Anorectal manometry
43
Disorders of defecation - faecal incontinence
Consistency of stool or frequency of movements Diseased bowel mucosa Reduced rectal capacity Pelvic floor disorder
44
Diagnostic testing for faecal incontinence
Endo-anal ultrasound Anorectal manometry
45
Anorectal manometry
Measures pressure generated by contraction of muscles