Physiology: Heart and blood Flashcards

1
Q

Which of ECG leads are unipolar?
Select one or more:
a) Augmented leads (AVR, AVL, AVF)
b) Wilson’s leads (V1-V6)
c) Standard leads (I, II and III)

A

A and B
Augmented leads (AVR, AVL, AVF)
Wilson’s leads (V1-V6)

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2
Q

Which ion influx causes slow diastolic depolarization in the pace-maker cells?
Select one or more:
a) Sodium through funny sodium channels
b) Potassium
c) Calcium through T channels
d) Sodium through fast sodium channels
e) Calcium through L channels

A

A and C
Sodium through funny sodium channels
Calcium through T channels

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3
Q

What is correct about the absolute refractory phase of the working myocardium
cell in the ventricle?
Select one or more:
a) During it threshold stimuli cannot excite the cell
b) During it only optimal suprathreshold stimuli can activate the cell
c) During it sodium can flow into the cell
d) During it inactivation gates of sodium voltage gated channels can be
closed
e) It is about 0,3-0,5 s long

A

A, C, D

  • During it threshold stimuli cannot excite the cell
  • During it sodium can flow into the cell
  • During it inactivation gates of sodium voltage gated channels can be
    closed
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4
Q

What is correct about the parasympathetic effect on the heart?
Select one or more:
a) Neurotransmitter released on the cardiac muscle cells is acetylcholine
b) It comes from first 4 thoracic segments of the spinal cord
c) It decreases heart rate
d) Receptor stimulated in the heart is beta 1
e) It increased force of contraction

A

A and C

Neurotransmitter released on the cardiac muscle cells is acetylcholine

It decreases heart rate

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5
Q

What is correct about the passive filling phase of the left ventricle?

Select one or more:
a) During it semilunar valves are open2
b) During it atria contract
c) During it atrioventricular valves are open
d) During it the more blood flows into the ventricle than in active filling
e) The fourth heart sound is heard in the beginning of it

A

C and D
- During it atrioventricular valves are open
- During it the more blood flows into the ventricle than in active filling

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6
Q

Calculate the cardiac output in ml/min from these parameters:
Heart rate 65 x/min
End diastolic volume 119 ml
Stroke volume 61 ml

A

Cardiac output is 3965 ml/min

(HR x SV)

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7
Q

Which from arterial blood pressure affecting factors can be directly influenced by
baroreceptor reflex?

Select one or more:
a) Viscosity of blood
b) Heart contractility
c) Circulating blood volume
d) Peripheral vascular resistance
e) Elasticity of aorta

A

B, C, D

Heart contractility
circulating blood volume
peripheral vascular resistance

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8
Q

What from mentioned is correct if the measured blood pressure in the brachial
artery is 140/65 mmHg?

Select one or more:
a) Systolic pressure is normal
b) Person might have large stroke volume
c) Diastolic pressure is normal
d) Pulse pressure is 100 mmHg
e) Person has high peripheral resistance

A

B and C

  • Person might have large stroke volume
  • Diastolic pressure is normal
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9
Q

The second heart sound is caused by:
Select one:
a) Ventricular filling
b) Closure of mitral and tricuspid valves
c) Closure of the aortic and pulmonary valves
d) Closure of the AV valve
e) Blood turbulence during contraction of atria

A

C
Closure of the aortic and pulmonary valves

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10
Q

What is normal pulse wave velocity in the leg arteries?
a) 0,15 - 0,2 m/s
b) 0,3 - 0,5 m/s
c) 5 - 6 m/s
d) 6 - 7 m/s
e) 7 - 8 m/s

A

E

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11
Q

What characterizes the coronary circulation?

Select one or more:
a) It receives about 200 ml/min of blood
b) It receives blood from the pulmonary trunk
c) It increases during physical activity
d) It is more intense in systole than diastole
e) It receives about 20% of cardiac output

A

A and C

  • It receives about 200 ml/min of blood
  • It increases during physical activity
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12
Q

When in indirect blood pressure measurement if pressure in cuff is slowly
decreased you will read the value of the diastolic blood pressure?

Select one or more:
a) In auscultatory method - when the first Korotkov’s sound will be heard
b) In auscultatory method - when the last Korotkov’s sound will disappear
c) In oscillometric method - at the time of highest oscillation
d) In palpatory method - when pulse disappears on the radial artery
e) In palpatory method - when pulse appears on the radial artery

A

B

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13
Q

Which substance does contract vascular smooth muscle cells?

Select one:
a) EDHF - Endothelium derived hyperpolarizing factor
b) Endothelins
c) Thromboxane A2
d) Leukotrienes
e) Serotonin

A

B, C, D, and E
Endothelins
Thromboxane A2
Leukotrienes
Serotonin

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14
Q

What is correct about the pulmonary circulation?

Select one or more:
a) Increase of partial pressure of carbon dioxide leads to dilation of arterioles
b) It receives blood from the aorta4
c) It delivers blood to alveolar capillaries
d) Arterial blood flows through veins
e) It receives 1-2% from the cardiac output

A

A, C and D
- Increase of partial pressure of carbon dioxide leads to dilation of arterioles
- It delivers blood to alveolar capillaries
- Arterial blood flows through veins

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15
Q

Which pressure increase can decrease filtration through the capillary wall?
Select one or more:
a) Colloid-osmotic pressure in the interstitium
b) Colloid-osmotic pressure in the capillaries
c) Colloid-osmotic pressure in the sub glycocalyx space
d) Hydrostatic pressure in the interstitium
e) Hydrostatic pressure in the capillary

A

B, C, and D
- Colloid-osmotic pressure in the capillaries
- Colloid-osmotic pressure in the sub
glycocalyx space
- Hydrostatic pressure in the interstitium

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16
Q

In the blood group test the agglutination was observed in the serum Anti-A and
Anti-B, but was not in the Anti-D and control serum. What is correct about the
determined blood group?

Select one or more:
a) There are anti-B agglutinins in this blood
b) This blood is rhesus negative
c) This blood can be transfused to B group person with the same rhesus blood
group
d) It is the most rare blood group in the AB0 system
e) There is D agglutinogen in this blood

A

B and D

  • This blood is rhesus negative

-It is the most rare blood group in the AB0 system

(distribution only 3%)

17
Q

What is correct about the hematocrit index?

Select one or more:
a) It is higher for males than females
b) It indicates volume of blood occupied by blood plasma
c) It decreases during blood donation
d) In females normally it can be 50%
e) It increases if person is dehydrated

A

A, C, and E

It is higher for males than females
It decreases during blood donation
It increases if person is dehydrated

18
Q

If blood pressure in carotid sinus is decreased:
(select the right option from the brackets)

Baroreceptors
[decrease/increase] activity

Impulse frequency to the cardiovascular control centre [decreases/increases]

Cardioacceleratory centre becomes [less/more]
active

Cardioinhibitory centre becomes [less/more]
active

Vasomotor centre becomes
[less/more]
active

Heart rate
[decreases/increases]

Blood vessels
[dilate/constrict]

A

If blood pressure in carotid sinus is decreased:
Baroreceptors
[decrease] activity

Impulse frequency to the cardiovascular control centre [decreases]

Cardioacceleratory centre becomes [more]
active

Cardioinhibitory centre becomes [less]
active

Vasomotor centre becomes
[more]
active

Heart rate
increases

Blood vessels
constrict

19
Q

What can increase probability of turbulent blood flow in a blood vessel?
Select one or more:

a) Greater speed of blood flow
b) Greater viscosity
c) Larger diameter of blood vessel
d) Higher blood pressure in blood vessel
e) Longer blood vessel

A

a) Greater speed of blood flow

c) Larger diameter of blood vessel

20
Q

Calculate the ankle brachial index for the 50 year old person (round to 2 decimal places, separate them with point/dot):

Heart rate 68 x/min
Blood pressure in the brachial artery 122/86 mmHg
Blood pressure in the ankle artery 102/67 mmHg

A

102/122=0,84

21
Q

How much is the normal pulse wave velocity in the leg arteries (any number in the normal interval; if decimal places are used, separate with a point/dot; provide units.

A

8m/s

22
Q

What can increase peripheral resistance to blood flow?

a) Greater viscosity of blood
b) Vasodilation
c) Lower pressure difference between both ends of the blood vessel
d) Longer blood vessel length
e) Increased concentration of proteins in blood

A

Increased concentration of proteins in blood
Greater viscosity of blood
….and?

23
Q

What characterizes the coronary circulation?
a. it receives about 700 ml/min of blood at rest
b. it increases during physical activity
c. it receives about 4 % of cardiac output at rest
d. it is more intense in diastole than systole
e. coronary arteries begin from pulmonary veins
f. It receives about 200 ml/min of blood at rest
g. It receives blood from the pulmonary trunk
h. It is more intense in systole than diastole
i. It receives about 20 % of cardiac output

A

bcdf

24
Q

When in indirect blood pressure measurement if pressure in cuff is slowly decreased you will read the value of the systolic blood pressure?
a. in auscultatory method - when the first korotkov’s sound will be heard
b. in auscultatory method - when the last korotkov’s sound will disappear
c. in oscillometric method - at the time of the first highest oscillation
d. in palpatory method - when pulse disappears on the radial artery
e. in palpatory method - when pulse appears on the radial artery

A

a, c,, d

25
Q

A sudden increase in afterload produces an increase in which of the following:
a) End diastolic volume in the next cycle
b) Stroke volume in current cycle
c) cardiac output
d) residual volume
f) End systolic volume

A

Increasing afterload not only reduces stroke volume, but it also increases left ventricular end-diastolic pressure (LVEDP) (i.e., increases preload). This occurs because the increase in end-systolic volume (residual volume remaining in ventricle after ejection) is added to the venous return into the ventricle and this increases end-diastolic volume. This increase in preload activates the Frank-Starling mechanism, which partially compensates for the reduction in stroke volume caused by the increase in afterload