physiology chapter 41 guyton Flashcards

1
Q

presence of hb in rbcs allows the blood to transport as much oxygen as could be transported in the form of dissolved oxygen in the water of blood

A

30 to 100 times

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2
Q

pressure of gaseous oxygen in alveolus averages

A

104 mm of hg

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3
Q

pressure of oxygen in venous blood entering the pulmonary capillaries at its arterial end averages only

A

40 mm of hg

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4
Q

initial pressure difference which causes the diffusion of oxygen from alveolus to pulmonary capillary

A

104-40= 64 mm of hg

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5
Q

partial pressure of oxygen in pulmonary capillary blood rises rapidly to almost to that of alveolar air by the blood has moved

A

a THIRD of a distance through capillary

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6
Q

during strenuous exercise a persons body may require as much as

A

20 times normal amount of oxygen

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7
Q

due to great cardiac output during exercise the time for which blood remains in the blood capillary may be reduced to

A

one half normal

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8
Q

diffusing capacity for O2 increases threefold during exercise due to

A

1) increased surface area of capillaries

2) ideal ventilation profusion ratio in upper part of lungs

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9
Q

blood becomes fully saturated with o2 during non exercising condition when it passes through

A

one third of capillary. only little oxygen is added during next two thirds

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10
Q

bronchial circulation

A

*2 percent of blood
*supplies maily the deep tissues of lungs
*not exposed to lung air
*called as SHUNT FLOW
*PO2 of shunt flow is 40 mm of hg
* causes the PO2 of blood to fall to 95 mm of hg fron
104 mm of hg

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11
Q

po2 in peripheral capillaries

A

95 mmof hg

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12
Q

interstitial PO2

A

40 mm of hg

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13
Q

blood leaving the tissue capillaries and entering the systemic veins has PO2

A

40 mm of hg

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14
Q

increasing the blood flow through a particular tissue

A

*increases the o2 transport between capillaries and tissues and hence increases the PO2 OF INTERSTITIAL FLUID

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15
Q

400% increase in blood flow than normal through a particular tissue

A

increases the po2 in interstitial fluid from normal of 40 mm of hg to 66 mm of hg

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16
Q

greater the metabolism of oxygen bt the cells

A

lesser will be the po2

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17
Q

po2 is determined by

A
  • transport of oxygen to tissues through blood

* the rate at which oxygen is used by cells

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18
Q

the intracellulae PO2 is always less thn peripheral capillaries because

A

02 is continuously being used the cells

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19
Q

intracellular po2 ranges from

A

minimum of 5mm of hg to maximum of 40 mm of hg

20
Q

average intracellular po2

A

23 mm of hg

21
Q

pressure normally required for full support of chemical processes that uses oxygen in the cells

A

1 to 3 mm of hg

22
Q

diffusion of co2

A

is 20x faster than the o2 and therefore less pressure difference is required for diffusion of co2

23
Q

intracellular Pco2

A

46 mm of hg

24
Q

interstitial Pco2

A

45 mm of hg

25
Q

pco2 of arterial blood entering the tissues

A

40 mm of hg

26
Q

pco2 of venous blood leaving the tissues

A

45 mm of hg

27
Q

pco2 of blood entering the pulmonary capillaries at its arterial end

A

45 mm o hg

28
Q

pco2 in alveoli

A

40 mm of hg

29
Q

pressure difference required to cause diffusion of co2 from pulmonary capillaries into alveoli is

A

5 mm of hg

30
Q

pco2 of pulmonary capillary blood falls to 40 mm of hg

A

after is has passed through ONE THIRD OF DISTANCE OF CAPILLARIES

31
Q

INCREASE IN TISSUE METABOLISM

A

INCREASES THE INTERSTIAL PCO2

32
Q

decrease in blood flow about one quarter

A

increases the pco2 from normal of 45 mm of hg to 60 mm of hg

33
Q

incresing blood flow six times

A

decreases pco2 from 45 mm of hg to 41 mm of hg nearly equal to alveolar pco2 of about 40 mm of hg

34
Q

10x increase in metabolic rate

A

increases pco2 considerably

35
Q

one quarter decrease in metabolic rate

A

decreases pco2 from 45 mm of hg to 41 mm of hg

36
Q

97 percent of oxygen is transported from lungs to tissues

A

in combination with hb

37
Q

3% of oxygen is transported

A

as dissolved in water of plasma of blood

38
Q

usual percent saturation of arterial blood

A

97% at 95 mm of hg

39
Q

usual percent saturation of hb in venous blood

A

75% at 40 mm of hg

40
Q

normal person contains about 15 grams of hb per 100 ml of blood if 1g hb combines with 1.34 ml of 02 how much oxygen is carried by 100 ml of blood

A

20.1 ml per 100 ml of blood (100% saturated)

also xpressed as 20 volumes percent

41
Q

the total quantity of o2 combined with normal systemic arterial blood

A

19.4 ml/100 ml of blood (97 % saturated at 95 mm of hg)

42
Q

the quantity of oxygen which remains bound to blood after it passes through tissue capillaries is

A

14.4 ml

43
Q

the quantity of oxygen transferred to tissues by each 100 ml of blood under normal conditions is

A

5ml

44
Q

during heavy exercise po2 in muscle cell interstitial fluid falls from 40 mm of hg to 15 mm of hg

A

only 4.4 ml of oxygens remains bound to hb under this pressure

45
Q

during exercise

A

15 ml of o2 is given to tissues by each 100 ml of blood