Physiology and Pharmacology Flashcards

1
Q

5 layers of the GI tract?

A
Serosa
Longitudinal smooth muscle
Circular smooth muscle
Sub mucosa
Mucosa
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2
Q

What are the two motor functions carried out by smooth muscle?

A

Segmentation

Peristalsis

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3
Q

What makes up the GI sphincters?

A

Thickened circular smooth muscle

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4
Q

What are the 3 phases of secretion?

A

Cephalic
Gastric
Intestinal

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5
Q

Name 5 pancreatic enzymes?

A
Trypsinogen
Amylase
Lipase
Chymotrypsinogen
Procarboxypeptidase
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6
Q

What is the function of HCL?

A

Activated pepsinogen to pepsin

Denatures proteins

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7
Q

What is the function of intrinsic factor?

A

Binds vitamin B12 to allow absorption

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8
Q

What is the function of histamine?

A

Stimulates HCL secretion

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9
Q

What is the function of Gastrin?

A

Stimulated HCL secretions

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10
Q

What is the function of somatostatin?

A

Stimulates HCL secretion

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11
Q

What stimulates release of bile?

A

Chyme in duodenum

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12
Q

How is bile released?

A

Gall bladder contracts
Sphincter of oddi opens
Bile spurts into duodenum via cystic and common bile ducts

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13
Q

5 functions of saliva?

A
Lubrication
Solvent
Anti bacterial
Digestion of carbohydrates
Neutralisation
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14
Q

What generates the basal electrical rhythm in the stomach and where?

A

Pacemaker cells in the fundus

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15
Q

What stimuli may delay gastric emptying?

A

Fat, acid, hypertonicity and distension of duodenum

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16
Q

What are bile salts secreted in response to?

A

CCK

17
Q

What enzyme in saliva digests carbohydrates?

A

alpha-amylayse