Physiology and Pharmacology Flashcards
5 layers of the GI tract?
Serosa Longitudinal smooth muscle Circular smooth muscle Sub mucosa Mucosa
What are the two motor functions carried out by smooth muscle?
Segmentation
Peristalsis
What makes up the GI sphincters?
Thickened circular smooth muscle
What are the 3 phases of secretion?
Cephalic
Gastric
Intestinal
Name 5 pancreatic enzymes?
Trypsinogen Amylase Lipase Chymotrypsinogen Procarboxypeptidase
What is the function of HCL?
Activated pepsinogen to pepsin
Denatures proteins
What is the function of intrinsic factor?
Binds vitamin B12 to allow absorption
What is the function of histamine?
Stimulates HCL secretion
What is the function of Gastrin?
Stimulated HCL secretions
What is the function of somatostatin?
Stimulates HCL secretion
What stimulates release of bile?
Chyme in duodenum
How is bile released?
Gall bladder contracts
Sphincter of oddi opens
Bile spurts into duodenum via cystic and common bile ducts
5 functions of saliva?
Lubrication Solvent Anti bacterial Digestion of carbohydrates Neutralisation
What generates the basal electrical rhythm in the stomach and where?
Pacemaker cells in the fundus
What stimuli may delay gastric emptying?
Fat, acid, hypertonicity and distension of duodenum