4th Year Gastro Flashcards
Where does UC always start?
The rectum
Where does UC never spread beyond?
Ileocecal valve
What is hepatic encephalopathy?
Liver failure causing a build up of toxins in the brain
What pattern of inheritance is Wilsons disease?
Autosomal recessive
What is Wilsons disease?
Excessive copper deposition
What happens to caeruloplasmin in Wilsons disease?
Decreases
What is used to induce remission in crohns disease?
Glucocorticoids
What are the 1st line drugs for maintaining remission in crohns disease?
Azatiohprine or Mercaptoline
What malignancy may cause a palpable gall bladder?
Pancreatic cancer
What is the incubation period of hep A?
15-50 days
Name 3 features of hep A?
Flu like prodrome
Jaundice
Hepatosplenomegaly
What is Zollinger Ellison syndrome?
Over secretion of gastric acid causing multiple gastroduodenal ulcers
What might be the cause of Zollinger Ellison syndrome?
MEN
Which anti bodies are present in autoimmune hepatitis?
ANA, anti smooth muscle anti body
Which anti bodies are present in primary biliary cirrhosis?
Anti mitochondrial anti body
What condition is primary sclerosis cholangitis associated with?
UC
Which anti bodies are present in primary sclerosis cholangitis?
ANCA and anti smooth muscle
How is hereditary haemochromatosis inherited?
Autosomal dominant
What is hereditary haemochromatosis?
Increase iron - raised ferritin
Bloody stools - UC or crohns?
UC
Virchows node?
Gastric carcinoma
What condition might cause a palpable gallbladder?
Pancreatic cancer - Courvoisier sign
What is achalasia?
Failures of relaxation of circular muscles at lower end of oesophagus
What is Plummer Vinson syndrome - 3 features?
Iron deficiency Glossitis Angular chelitis Dysphagia due to cricoid web pre malignant
Name 1 cause of pre hepatic jaundice?
Haemolysis
Haemolytic anaemias
Name 2 causes of hepatic jaundice?
Acute liver failure, alcoholic, hepatitis, cirrhosis
Name 2 causes of post hepatic jaundice?
Biliary atresia, gallstones, CBD, strictutres, tumours
Pre hepatic jaundice - stool and urine colour?
Stool - Normal
Urine - normal
Hepatic jaundice - stool and urine colour?
Stool -Normal
Urine - dark
Post Hepatic jaundice - stool and urine colour?
Stool - pale
Urine - dark
What is the most common cause of genetic elevated bilirubin and how is it inherited?
Gilberts syndrome - autosomal recessive
In what age group might a raised Alk phos be physiological?
Teenagers
Episcleritis and uveitis - UC or crohns?
Episcleritis - CD
Uveitis - UC