physiology + anatomy Flashcards
1
Q
what are adrenaline and tryptophan derived from
A
tyrosin + trytophan
2
Q
are amino acids hydrophilic or hydrophobic
A
hydrophilic
3
Q
how to calculate plasma concentration
A
PC = rate of secretion - rate of elimination
4
Q
when do hormones become deactivated
A
when they are bound to a receptor
5
Q
where is insulin peptide synthesised
A
RER of pancreatic B cells as larger preprohormone - preproinsulin
6
Q
structure of insulin
A
2 polypeptide chains linked by disulphide bonds
connecting C peptide (no physiological function)
7
Q
mutation in kir6.2
A
neonatal diabetes (give SURs)
8
Q
what happens when insulin in bound to the a subunit
A
B subunits phosphorylase and dimerise -> activating the catalytic activity of the receptor
9
Q
where are ketone bodies formed
A
liver mitochondria
