Physiology Flashcards

1
Q

What type of receptors cause taste and smell

A

Chemoreceptors

Stimulated by binding to particular chemicals

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2
Q

Taste receptors influence smell - true or false

A

False

other way around

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3
Q

How does our sense of taste and smell protect us

A

Acts as a quality control for what we eat

e.g. most poisons are bitter and gone off food is sour/acidic

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4
Q

Where in the body is the sensation of taste received

A

Sensory receptor cells are packaged into the taste buds

They are present in the tongue, palate, epiglottis and pharynx

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5
Q

Describe the lifespan of a taste receptor cell

A

Life span of around 10 days

They are replaced by basal cells in the taste buds continuously

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6
Q

How does the sensation of taste reach the brain

A

Binding of chemicals causes depolarising receptor potential
The receptor cells synapse with afferent nerve fibres which carry AP’s
Signals are sent by cranial nerves via brainstem and thalamus to the cortical gustatory area

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7
Q

Where are most of the taste buds found

A

In the papillae in the tongue

In the fungiform, vallate and foliate types

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8
Q

Which afferent nerve fibres (specifically) transmit taste to the brain

A

Chorda tympani of facial nerve - anterior tongue
Glossopharyngeal nerve - posterior tongue
Vagus nerve - areas outwith tongue

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9
Q

What are the 5 primary tastes

A
Salty - stimulated by NaCl 
Sweet - glucose 
Bitter - diverse group 
Sour - H+ ions (acid) 
Umami - meat or savoury triggered by amino acids
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10
Q

What is ageusia

A

Loss of taste function

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11
Q

What can cause loss of taste

A

Nerve damage
Local inflammation
Some endocrine disorders

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12
Q

What is hypogeusia

A

Decreased sense of taste

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13
Q

What can cause reduced sense of taste

A

Chemotherapy

Certain medications

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14
Q

What is dysgeusia

A

Distortion of taste

Many causes

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15
Q

What cell types are found in the olfactory mucosa

A

Olfactory receptor cells
Supporting cells
Basal cells

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16
Q

Describe how smell is sensed

A

Odorants bind to cilia on the surface of the olfactory mucosa
This stimuli passes up to the olfactory rods (thickened dendrite)
These rods come together to form the afferent fibres of the olfactory nerve
The nerve pierces the cribiform plate of ethmoid bone and enter the olfactory bulbs in the brain
The bulb passes info along the olfactory tract to the temporal lobe and olfactory areas of the brain

17
Q

How long do olfactory receptor cells live

A

Around 2 months

18
Q

What properties must a substance have in order to be smelled

A

Must be sufficiently volatile - some particles must enter the nose with air

Must be sufficiently water soluble - can dissolve in mucus

19
Q

How does sniffing enhance smell

A

Draws air upwards in the nasal cavity which helps it reach the olfactory mucosa

20
Q

What is anosmia and what can cause it

A

The inability to smell

Viral infection, allergy, polyps and head injury can cause it

21
Q

What is hyposmia and what can cause it

A

Reduced ability to smell
Similar causes to anosmia (injury, infection)
May be early sign of Parkingson’s