Physiology Flashcards
upper GI function
intake source and receptacle
initial digestion occurs
middle GI function
site where most of digestion and absorption occurs
lower GI tract function
storage channel for elimination of waste
4 layers of of GI wall +fxn
inner mucosal
submucosal (support)
muscularis (peristalsis, circular layer, longitudinal layer)
outer serosa
types of muscle contractions
mass movements tonic contractile phasic contractile segementing haustral
peristalsis contractile activity
serves to propel forward food
mass movements
propulsive movement of unit within large intestine
tonic contractile activity
found between two organs, stable contraction
occludes lumen
typically in LES, UES, other sphincter
phasic contractile activity
periodic contraction
lasts few seconds and followed by relaxation
segmenting contractions
mix chyme with secretions and bring contents into contact with mucosa for digestion and absorption
haustral contractions
segmenting contraction with longer duration
components of enteric nervous system
myenteric plexus
submucosal plexus
myenteric plexus
aka Auerbach
between circular and longitudinal calls
concerned with motility
submucosal plexus
AKA Meissner
controlling function of ea. segment of intestinal tract
SNS effect on GI tract
via thoracocolumbar spinal cord
stimulation cause decrease in activity + decreased motility and secretions
PNS effect on GI tract
via vagus nerve
cause increase in activity including increased motility and secretions
areas of striated muscle in GI
pharynx, upper third of esophagus, external anal sphincter
increased smooth muscle ocontraciotn when
PNS stimulation
stretching smooth muscle (gas or constipation)
decreased excitability of smooth muscle contraction
SNS stimulation
achalasia and neuromuscular
LES does not rely
Hirschsprung dz and neuromuscular
lack of inhibitory enteric n. in colon
ileus and neuromuscular
caused by trauma or infection + disruption of normal neuro hormonal regulation
IBS and neuromuscular
altered sensory nerve fxn or altered motility
involuntary motor impulses for oral and pharyngeal phases carried in: 4
- trigeminal (V)
- Glossopharyngeal (IX)
- Vagus (X)
- hypoglossal (XII)
impulses for esophageal phase are carried in
vagus (X)
rectosphinteric reflex
responsible for defecation
contents cause relaxation of internal anal sphincter and urge to defecate occurs
functions of saliva
- protection and lubrication
- protective antimicrobial action
- initiate digestion of starches
salvia produced and secreted by
parotid, submaxillary, sublingual and buccal glands
gastric secretion (cells) (4)
mucous secreting cells
parietal cells
cheif cells
G sells
mucous secreting cells
barrier of protection
parietal cells
HCl and IF (b12)
chief cells
pepsinogen (converted to Pepsi when exposed to low pH)
G cells
secrete gastrin
stimulates gastric acid and pepsinogen, increased gastric blood flow, stimulate scontraction, growth of gastric and intestinal mucosal cells
functions fo secretory glands
mucous production (lubricate, protect)
secrete fluids and enzymes (digestion of nutrients)
GI hormones
cholecystokinin
gastrin
secretin
cholecystokinin
stim cox of GB
secretion of enzymes, slows gastric emptying, decreases food intake
gastrin
stimulates secretion of gastric acid and pepsinogen
increases gastric blood flow, simulates gastric smooth muscle and stimulates growth of gastric and intestinal cells
secretin
stimulates secretion of bicarbonate
contains fluids by pancreatic and liver
secretions of small intstine
bruners glands (alkaline mucous)
secretion 2
secretion 3 (enzymes peptidases and disaccharidases)
functions of gut flora
metabolic activity (fermentation of indigestible)
trophic effects /grooming
protection
colonization
when does colonization take place?
begins shortly after birth
influenced by passage thru birth canal and others
digestion
dismantling food into constituent parts
processes of digestion
hydrolysis
enzyme cleavage
fat emulsification
absorption
process of moving food into the internal environment
active transport and diffusion
fxn of intestinal brush border
aid in digestion of carbs and proteins
adhere to border of villous structure