Malignancy App Flashcards
2 different types of esophageal Carcinoma + site
SCC - proximal and middle
Adenocarcinoma - distal
why does SCC spread rapidly?
esophagus lymph nodes are located in the lamina propria + esophagus lacks serosa so it can directly spread and quickly get into the lymph nodes
CA risk factor for
Hammartomatous polyp
intermediate risk
CA risk factor for
Hyperplastic polyp
low - no risk
CA risk factor for adenomatous polyps
High risk
polyp with gravest risk of CA
Tubulovillous is the gravest risk
types of adenomatous polyps
Tubular, villous, tubulovillous
high risk
local SCC esophageal cancer spread
gravest risk
erosion into the aorta causing massive upper GI hemorrhage
Esophageal CA belt
location + type
Caspian sea through china,
elevated risk of cancer of the esophagus
SCC - 90%
why do we think esophageal CA belt is predisposed?
poor nutritional status
low fruit/veggies diet
beverages high in temp
smoking
SCC risk factors
- tobacco
- alcohol
- low fruits and veggies
- Nitroasamine compounds
- achalasia
nitrosamine compounds
risk factor for BOTH esophageal and gastric CA
cured meats (bacon)
Japanese fish
pickled food
beer
why is achalasia a risk factor for esophageal CA
increased contact time of harmful food due to constriction
