Physiology Flashcards
What is the electrical conduction system?
Specialised cardiac cells generate their own action potential/electical currents that stimulate the heart to contract and relax
They are electrically unstable - discharge impulses rapidly and regularly
What is the pathway for the electrical conduction system?
SA node
AV node
Bundle of his
Two bundle branches
Purkinje fibres
What happens when the SA node transmit a signal?
Atria contract
Transmitted to AV node
Why does the AV node delay electrical transmission?
To ensure atria have completely contracted
What is stroke volume?
The amount of blood the heart pumps out each ventricle each heartbeat
What is cardiac output?
The amount of blood the heart pumps out in one minute
What is the equation for cardiac output?
Stroke volume x heart rate
What are the three factors that regulate stroke volume?
- Preload
- Force of contraction
- Afterload
What is preload?
The amount of stretch in the cardiac muscle relates to the force they contract during systole
The stretch relates to how much blood is in the ventricle before the next contraction and this is dependent on venous return
The more the ventricles fill, the more the muscle will stretch resulting in stronger force of contraction which increases stroke volume and cardiac output
What is force of contraction?
Strong contractions increase stroke volume
Can be affected by hormones
Sympathetic nervous system increases force
What is afterload?
Refers to the pressure in the arteries that the ventricles must overcome in order to eject blood
An increase in arterial pressure increases afterload, making it more difficult for ventricles to pump blood
What sets the heart rate?
SA node
What can change heart rate?
NS activated -
Sympathetic nerves release noradrenaline which leads to excitation of SA
Parasympathetic releases acetylcholine and reduces impulses in the SA
What is BP?
Force or pressure which blood exerts of the wall of the blood vessels when the ventricles contract
What is a healthy BP?
120/80