physiology Flashcards
what ion channels are involved in depolarisation/excitation?
funny Na+ channel- If
transient T-type Ca2+ channels
long-lasting L-type Ca2+ channels
what ion channels are involved in repolarisation/relaxation?
voltage-gated K+ channels
on an ECG which leads + vessel correlate for inferior?
II + III + aVF
RCA
on an ECG which leads + vessel correlate for anterolateral?
I + aVL + V5 + V6
Left circumflex
on an ECG which leads + vessel correlate for anteroseptal?
V2 + V3 + V4
LAD
on an ECG which leads + vessel correlate for anterior?
V2 + V3 + V4 + V5 + V6
Left main stem
on an ECG which leads + vessel correlate for posterior?
V1 + V2 + V3 reciprocal
RCA
what are the causes of right axis deviation?
anterolateral MI
RVH
PE
Lposterior hemiblock
WPW
ASD secundum
what are the causes of left axis devation?
inferior MI
LVH
Lanterior hemiblock
WPW
ASD primum
what is p mitrale?
bifid p waves = left atrium hypertrophy
what can cause p mitrale?
HTN
aortic stenosis
mitral regurgitation
mitral stenosis
what is p pulmonale?
peaked p waves = right atrium hypertrophy
what can cause p pulmonale?
pulmonary HTN
COPD
tricuspid stenosis
what classes a wide QRS?
> 120ms
what classes a pathological Q wave?
> 1mm wide and >2mm deep
means full thickness MI
what are the signs of RVH on an ECG?
dominant R wave in V1
deep S wave in V6
what are the signs of LVH in an ECG?
R wave in V6>25mm
R wave in V5/6 + S wave in V11 >35mm
what is a normal PR interval?
120-200MS
(start of P wave to start of QRS)
what are the causes of a short PR interval?
accessory conduction eg WPW
nodal rythm
HOCM
what is a normal QTc?
380-420ms
(start of QRS to end of T wave)
what are the causes of short QTc?
digoxin
beta blockers
phenytoin
what are the causes of long QTc?
TIMME
toxines- macrolides, antiarrythmics quinidine, amiodarone, TCAs, histamine antagonists
inherited- romano-ward, jervell
Ischaemia
myocarditis
mitral valve prolapse
electrolytes- low mag/k/ca/temp
what leads are T waves normally inverted in?
aVR + V1
what are the features of RBBB on an ECG?
maRRow
wide QRS
RSR pattern in V1