old HF, pulmonary oedema, cardiogenic shock, HTN Flashcards
what is the definition of heart failure?
CO inadequate for body’s requirements despite adequate filling pressures
what is the pathophysiology of HF?
1) reduced CO initially -> compensation starling effect dilates heart to enhance contractility remodelling -> hypertrophy RAS + ANP/BNP release sympathetic activation
2) progressive decrease in co-> decompensation
progressive dilatation leads to impaired contractility + functional valve regard
hypertrophy leads to relative myocardial ischaemia
RAS activation leads to na+ and fluid retention leads to increase venous pressure leads to oedema
sympathetic excess leads to increase in afterload and decrease in CO
what is low output HF?
CO decreases and fails to increase with exertion
what are the cateogires of causes of low output HF?
1) pump failure
2) excessive pre-load
3) excessive afterload
what are the causes of pump failure in low output hf?
1) systolic failure leads to impaired contraction ischaemia/MI dilated cardiomyopathy HTN myocarditis
2) diastolic failure leads to imapired filling
pericardial effusion/tamponade/constriction
cardiomyopathy: restrictive, hypertrophic
3) arrhythmias- bradycardia, heartblock, tachycardias, anti-arrhythmics eg bb, verapamil
what are the causes of excessive preload in low output hf?
AR
MR
fluid overload
what are the causes of excessive afterload in low output hf?
AS
HTN
HOCM
what is high output hf?
there are higher needs which lead to RVF initially and then LVF
what are the causes of high output hf?
anaemia, AVM
thyrotoxicosis, thiamine deficiency (beri beri)
pregnancy, pagets
what are the causes of right ventricular dysfx?
LVF
co pulmonale
tricuspid pulmonary valve disease
what are the symptoms of RVF?
anorexia and nausea
what are the signs of RVF?
raised jvp + jugular venous distension
tender smooth hepatomegaly (may be pulsatile)
pitting oedema
ascites
what are the causes of LVF?
IHD idiopathic dilated cardiomyopathy systemic HTN mitral and aortic valve disease specific cardiomyopathies
what are the symptoms of LVF?
fatigue exertional dyspnoea orthopnoea + PND nocturnal cough (+/- pink frothy sputum) weight loss + muscle wasting
what are the signs of LVF?
cold peripheries +/- cyanosis often in AF cardiomegaly with displaced apex S3 + tachy= gallop rythm wheeze (cardiac asthma) bibasal creps
what is acute HF?
new onset or decompensation of chronic
peripheral/pulmonary oedema
+/- evidence of peripheral hypoperfusion
what is chronic HF?
develops/progresses slowly
venous congestion common
arterial prssure mainted until very late
how is chronic HF diagnosed?
framingham criteria
2 major criteria or 1 major + 2 minor
what investigations woudl you do for chronic hf?
bloods- FBC, UE, BNP, FT, glucose, lipids
CXR
ECG
ECHO
what would you see on CXR for chronic hf?
ABCDEF alveolar shadowing kerley b lines cardiomegaly upper love divesion effusions fluid in fissures
what can you see on ECG for chronic heart failure?
ischaemia
hypertrophy
AF
what can be seen on echo for chronic heart failure?
focal/global hypokinesia
hypertrophy
valve lesions
intracardiac shunts
global systolic/diastolic function. EF normally about 60%
what classification system is used for hf?
NYHA classification
1- no limitation of activity
2- comfortable at rest, dypsnoea on ordinary activity
3- marked limitation of ordinary activity
4- dyspnoea at rest and all activity
what is the primary/secondary cardiovascular risk prevention for HF?
smoking cessation decrease salt intake weight loss/gain- dietician rehab programme aspirin statins
what is the underlying cause for chronic heart failure requiring treatment?
valve disease
arrhytmias
ischaemia
what are the exacerbating factors for chronic heart failure requiring treatment?
anaemia
infection
increased bp
what treatments lower mortality in chronic heart failure?
ace inhibitors
bb
spironolactone