Physiological stress

Question 1

Typical clinical presentation

Answer 1

acute onset pain in right iliac fossa
nausea, vomiting, fever
rebound tenderness at McBurney's point
guarding
positive Rovsing's sign

Question 2

what is the typical physiological response to appendicitis

Answer 2

increased glucagon secretion

Question 3

What are the physiological responses to stress

Answer 3

increased glucose secretion, increased oxygen, increased sympathetic activity

Question 4

What is the hypothalamic-pituitary-adrenal axis role during stress

Answer 4

increased production of CRH which stimulates production of ACTH, which in turn stimulates production of cortisol.

Question 5

What is the role of cortisol in stress

Answer 5

Cortisol has an important role in the stress response of releasing glucose from fat storage. So, the ACTH level would be increased, not reduced.

Question 6

During physiological stress, what happens to T4 levels?

Answer 6

DROPS

Question 7

What is T4 a modulator of

Answer 7

metabolic rate

Question 8

What are the features of the acute phase response to injury

Answer 8

Reduction of transport proteins (albumin, transferrin)
Pyrexia
Hepatic sequestration cations
Increased serum amyloid A