Addison's disease Flashcards
1
Q
Main features of Addison’s
A
reduced cortisol, reduced aldosterone
2
Q
Addison’s disease causes what disturbance of potassium?
A
Hyperkalaemia
3
Q
Aldosterone is a mediator of what
A
potassium balance
4
Q
Features of Addison’s disease
A
lethargy, vomiting, weakness, salt cravings, hypertension hypoglycaemia hyper pigmentation - palmar creases loss of pubic hair in women hyponatraemia and hyperkalaemia crisis = shock, pyrexia, collapse
5
Q
What are other causes of hypoadrenalism
A
Primary causes tuberculosis metastases (e.g. bronchial carcinoma) meningococcal septicaemia (Waterhouse-Friderichsen syndrome) HIV, antiphospholipid syndrome
Secondary causes pituitary disorders (e.g. tumours, irradiation, infiltration)
6
Q
What addison’s is associated with hyperpigmentation?
A
Primary
