Physiological changes in pregnancy Flashcards
Uterus Weight ↑ or ↓
↑
Cervix, hardens or softens
softens
Blood - volume, Hb, WCC
↑ Volume but ↓ Hb relatively, ↑WCC
How much is VTE risk increased by?
6x
↑ clotting factors, ↓fibrinolytic activty, ↑ stasis
Cardiac Output ↑↓?
↑ by about 40% - basically pumping for 2
BP? ↑ or ↓
BP ↓ in mid pregnancy then rises back up again towards end
GRF? ↑ or ↓?
↓ GFR by ~40%
Recreation drugs
Which are teratogenic?
Cocaine and ecstasy
REactional dugs
facial clefts, neonatal hypotonia & withdrawal
Benzos
Which anti-epileptics to use and not use?
Carbamazepine and lamotrigine alright
Valproate bad
What type of delivery with cardiovascular disease?
Forceps, normal may be too difficult for Pt. Also may need to give Abx for endocarditis
What do you give for antiphospholipid?
Aspirin and LWMH
Vaginitis during pregnancy? Whats the infection?
Candidiasis
itchy, great white discharge,
Treat with clotrimazole pessary
Abdo pain - how common is it what could cause it?
Very common
Appendicitis/pacreatitis, UTI, fibroids