Physiological Flashcards

1
Q

In the peripheral nervous system, the neurotransmitter _____ is released into the neuromuscular junction, where is causes muscles to contract; and, in the central nervous system, it’s involved in the regulation of the sleep-wake cycle and learning and memory

A

Acetylcholine (ACh)

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2
Q

Elevated levels of ______ contribute to Schizophrenia, Autistic disorder, and food restrictions associated with Anorexia Nervosa, while low levels play a role in aggression, depression, suicide, Bulimia Nervosa, PTSD, and OCD

A

Serotonin

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3
Q

Benzodiazepines reduce anxiety by enhancing the effects of ________

A

GABA

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4
Q

The peripheral nervous system (PNS) is divided into the _____ nervous system, which carries information between the CNS and the body’s sensory systems and skeletal muscles, and the _______ nervous system, which regulates the activities of the visceral muscles and glands.

A

somatic; autonomic

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5
Q

The autonomic nervous system has two subdivisions: the ______ branch prepares the body for “fight or flight,” while the _______ branch is associated with the conservation of energy and states of rest and relaxation

A

sympathetic; parasympathetic

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6
Q

Computed tomography (CT) and magnetic resonance imaging (MRI) provide information on the ______ of the brain, while _____, SPECT, and fMRI provide information on the brain’s _____ activities

A

structure; PET; functional

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7
Q

Memory loss associated with Alzheimer’s dementia has been most consistently linked to abnormal levels of which neurotransmitter?

A

Acetylcholine

(ACh has been implicated in memory loss associated with Alzheimer’s dementia. More specifically, degeneration of cholinergic (ACh) cells in the entorhinal cortex and other areas that communicate directly with the hippocampus has been linked to this disorder.)

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8
Q

Regional cerebral blood flow (rCBF) serves as an index of neural activity when using what technique?

A

PET

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9
Q

What is most likely to be useful for treating Obsessive-Compulsive Disorder?

A

a drug that blocks the reuptake of serotonin

SSRIs and sometimes TCAs

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10
Q

The ______ mediates the sleep-wake cycle and other circadian rhythms

A

SCN (suprachiasmatic nucleus)

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11
Q

The ______ are important in planning, organizing, and coordinating voluntary movements.

A

basal ganglia

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12
Q

The limbic system is associated primarily with emotional activities. The amygdala attaches emotions to ______,, and damage to the amygdala and temporal lobes can produce _____ syndrome, which is characterized by reduced fear and aggression, psychic blindness, and hypersexuality

A

memories; Kluver-Bucy

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13
Q

The right and left hemispheres of the cerebral cortex are connected by several bundles of fibres, the largest is the ________

A

corpus callosum

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14
Q

While both hemispheres play a role in most behaviours, the ______ (usually left) hemisphere is primarily responsible for language, ______ memory, and ______ emotions, while the ____ (usually right) hemisphere governs _____ recognition, nonverbal memory, and _____ emotions

A

dominant; verbal; positive; non-dominant; facial; negative

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15
Q

When a familiar object is presented to the _____ visual field of a split-brain patient, the patient can name the object but cannot pick it out with his/her _____ hand

A

right; left

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16
Q

Damage to specific areas of the prefrontal cortex may produce one of three syndromes: Damage to the dorsolateral area results ______ syndrome; damage to the orbitofrontal area produces disinhibition syndrome, which is also known as ______, and damage to the mediofrontal area produces apathetic syndrome, which is also referred to as ______

A

dysexecutive; pseudopsychopathy; pseudodepression

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17
Q

Lesions in the left parietal lobe may produce ____ syndrome, which involves a combination of finger agnosia, right-left confusion, agraphia, and acalculia

A

Gerstmann’s

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18
Q

The temporal lobes contain the ______ cortex and _____ area and are involved in the encoding, retrieval, and storage of long-term _____ memories

A

auditory; Wernicke’s; declarative

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19
Q

An adult with damage to his hippocampus can be expected to:

A

forget events that occur after the accident that caused the damage

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20
Q

A split-brain patient is staring straight ahead when the word “headband” is flashed directly in front of her. The woman will most likely report seeing which of the following?

A

band

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21
Q

Damage to _______ would most likely result in impairments in the organization and coordination of voluntary motor responses?

A

basal ganglia

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22
Q

Following a head injury, a women exhibits dressing apraxia and tactile agnosia and doesn’t comb the hair on the left side of her head. Which area of her brain has most likely been damaged?

A

Parietal Lobe

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23
Q

Depth perception depends on a combination of binocular and monocular cues. _____, one of the binocular cues, refers to the fact that our two eyes see objects in the world from two different views, and, the closer an object, the greater the disparity of the two images

A

retinal disparity

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24
Q

Of the senses, ______ is the only one that is not linked to a single type of stimulus

A

pain

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25
According to ______ theory, the perception of pain can be blocked by special cells in the spinal cord
gate-control
26
_____ is a rare condition in which the stimulation of one sensory modality triggers a sensation in another sensory modality
Synesthesia
27
According to ______ Law, the more intense the stimulus, the greater the increase in intensity needed to produce a just noticeable difference
Weber's
28
Fechner's Law proposes that physical stimulus changes are _____ related to their psychological sensations; and, according to ______ Law, sensation is and exponential function of stimulus intensity
logarithmically; Steven's Power
29
According to __________, sensation is an exponential function of stimulus intensity.
Steven's Power Law
30
Gate control theory is useful for:
identifying methods for controlling pain
31
Retinal disparity helps explain:
depth perception for objects that are close
32
Following bilateral medial temporal lobectomy the relieve severe epilepsy, H.M was able to recall remote events, but he exhibited severe _____ amnesia and retrograde amnesia for _____ events
anterograde; recent
33
A number of areas of the brain play an important role in learning and memory. The _____ lobes are essential for the storage and retrieval of long-term declarative memories; The _______ is involved in memory consolidation and explicit memory; and the ______ attaches emotion to memory
temporal; hippocampus; amygdala
34
The _____ cortex plays a role in episodic memory, prospective memory, and working memory, while the ____, cerebellum, and motor cortex contribute to procedural and implicit
prefrontal; basal ganglia
35
At the neural level, ____ in the hippocampus is believed to be important for long-term memory. There is also evidence that long-term memory depends on increased _____ during the minutes or hours following training
long-term potentiation (LPT); protein synthesis
36
when the synthesis of protein or _____ is inhibited at the time of training, long-term memory is impaired
RNA
37
_____ aphasia results from damage to the arcuate fasciculus and involves _____ (an inability to name a familiar object, attribution, or action), paraphasia, and impaired repetition
Conduction; anomia
38
H.M. underwent a bilateral medial temporal lobectomy as treatment for severe epilepsy. Following the surgery, H.M. exhibited which of the following?
impairments in recent long-term memory
39
Long-term potentiation (LTP) is believed to underlie:
learning and memory
40
According to _____ theory, emotions reflect perceptions of bodily reactions ("I'm scared because me knees are shaking"), while ____ theory proposes that emotion-provoking stimuli simultaneously produce a subjective emotional experience and bodily reactions
James-Lang; Cannon-Bard
41
Lazarus's cognitive appraisal theory proposes there are differences in how emotion-arousing events are interpreted or appraised and distinguishes between three types of appraisal: ____, ____, and ______
Primary, secondary and re-appraisal
42
Primary appraisal refers to a person's evaluation of a ______ as irrelevant, positive-benign, or stressful with regard to his or her own well-being
situation
43
secondary appraisal refers to the person's evaluation of the ______ he or she has to cope with a situation that has been identified as stressful
resources
44
_______ occurs when the person monitors the situation and, as necessary, modifies his or her primary and/or secondary appraisals
re-appraisal
45
_____ circuit was proposed in 1937 as a neural circuit that mediates the experience and expression of emotion
Papez's
46
The _____ hemisphere governs positive emotions and damage to this area results in _______
left (dominant); catastrophic reactions
47
The ______ hemisphere mediates negative emotions, and lesions produce _____, emotional lability, and/or undue cheerfulness
right; indifference and apathy
48
Electrical stimulation of the amygdala can produce a _______ and/or rage response, while damage to the hypothalamus can result in rage or uncontrollable ______
fear; laughter
49
Seley's general adaptation syndrome describes the stress response as involving three stages: _____, _____, and ______
alarm reaction, resistance, exhaustion
50
Sleep stages 3 and 4 are characterized by large, slow _____ waves
delta
51
The fifth stage is marked by the presence of _____. Because the sleeper is both in a deep state of sleep and physiologically active, this stage is also referred to as active or ____ sleep
rapid eye movements; paradoxical
52
Alpha waves are replaced by theta waves during ________ sleep.
Stage 1
53
Traumatic brain injury (TBI) may be the result of either a closed- or open-head injury. A closed head injury usually causes an alteration or loss of ______ and some degree of anterograde and retrograde amnesia
consciousness
54
The term posttraumatic amnesia is usually used to refer to _______ amnesia
anterograde
55
When retrograde amnesia occurs, _______ memories return first
remote (distant past)
56
Recovery from TBI is moderated by a number of factors, but, in general, the greatest amount of recovery occurs during the first _____ months
three
57
As described in the DSM-5, the diagnosis of Neurocognitive Disorder Due to Traumatic Brain Injury requires that symptoms meet the criteria for Major or Mild neurocognitive disorder plus evidence of a traumatic brain injury with loss of _____, ______, disorientation and confusion, and/or neurological signs
consciousness; posttraumatic amnesia
58
When the stroke involves the ____ cerebral artery, symptoms may also include dysarthia, aphasia, or apraxia
middle
59
Huntington's disease is due to an _____ dominant gene and is characterized by a combination of psychiatric, cognitive, and motor symptoms
autosomal
60
Huntington's disease has been linked to degeneration of ______-secreting cells and glutamate excitotoxicity in certain structures of the basal ganglia
GABA
61
_____ seizures begin in one side of the brain and affect one side of the body, at least initially.
partial
62
Hyposecretion of ADH by the pituitary results in ______
diabetes insipidus
63
Too much thyroxine produces _____, which is characterized by speeded-up metabolism, _______ body temperature, weight loss, agitation, and insomnia
hyperthyroidism; elevated
64
Too little thyroxine results in ______, which involves slowed metabolism, weight gain, lowered body temperature, depression, lethargy, and impaired _____
hypothyroidism; memory and concentration
65
Too little insulin can produce ______
diabetes mellitus
66
A young woman says that she always feels cold, is frequently depressed and has trouble concentrating, is lethargic and has lost interest in sex, and has gained weight even though she doesn't eat much. These symptoms are most suggestive of what endocrine disorder?
hypothyroidism
67
Research on symptoms associated with Parkinson's disease suggests that depression:
may be endogenous to the disease rather than just a reaction to it.
68
Agonist
produce effects similar to those produced by a neurotransmitter
69
Antagonist
produce no activity on their own but reduce or block the effects of a neurotransmitter
70
anticholinergic effects
dry mouth, blurred vision, urinary retention, constipation, and tachycardia
71
a rare, life-threatening side effect of first generation antipsychotics-- characterized by a rapid onset of muscle rigidity, tachycardia, hyperthermia, and altered consciousness
Neuroleptic malignant syndrome (NMS)
72
catecholamine hypothesis
some forms of depression are caused by a deficiency of norepinephrine while mania is due to excessive norepinephrine. 
73
Anticholinergic side effects 
dry mouth, blurred vision, urinary retention, constipation, and tachycardia
74
TCAs are also _____ and can cause hypertension, extreme hypotension, and tachycardia
cardiotoxic
75
SSRIs are less cardiotoxic than the TCAs, are safer in _____ and are less likely to produce ____ impairments
overdose; cognitive
76
The most dangerous side-effect of MAOIs is hypertensive crisis, which can occur when an MAOI is taken in conjunction with certain drugs or food containing ______
Tryamine
77
To avoid toxicity when taking lithium, patients must be careful to avoid fluctuations in their _____ intake and to avoid caffeine, alcohol, and other diuretics
salt (sodium)
78
Carbamazepine is an _____ drug that has been found to have similar effects on manic symptoms as lithium and may be more beneficial than lithium for people who experience ____ or who have dysphoric mania
anticonvulsant; frequent mood swings
79
Cross-tolerance 
occurs when tolerance to one drug produces tolerance to other drugs in the same class
80
Propranolol and other beta-blockers are used to treat cardiovascular disease, tremor, and migraine headache and have been useful for reducing the ______ symptoms of anxiety
physical
81
Amphetamines are currently used to treat ______ and ADHD, while methylphenidate is used to treat the latter disorder
narcolepsy
82
Common side-effects of methylphenidate include decreased ______, insomnia, and dysphoria
appetite
83
Higher doses of methylphenidate may cause ____ suppression, but occasional _____ can help minimize this effect
growth; drug holidays
84
Drugs that block the activity of __________ produce dry mouth, blurred vision, postural hypotension, urinary retention, and tachycardia
ACh
85
In comparison to the tricyclics, fluoxetine and other SSRIs are less ______
cardiotoxic
86
Hypothyroidism
caused by hyposecretion of thyroid hormones - decreased rate of metabolism, reduced appetite with weight gain, slowed heart rate, lowered body temperature, cold intolerance, depression, lethargy, decreased libido, confusion, and impaired concentration and memory
87
Hyperthyroidism
caused by hypersecretion of thyroid hormones, and its symptoms include an increased rate of metabolism, elevated body temperature, heat intolerance, increased appetite with weight loss, accelerated heart rate, insomnia, emotional lability, and reduced attention span. 
88
Loss of __________ neurons in the __________ is believed to contribute to depression and cognitive impairment in patients with Parkinson’s disease.
dopamine; striatum