Physiologic changes in aging Flashcards
What factors influence aging
- chronologic age
- nutrition
- environmental exposure to risk factors
- illness
- injury
- social support
- hromone replacement
what does Senescence mean
term that means predictable age related changes as opposed to those casued by disease
What is Homeostenosis
reduction in the ability to maintain homeostasis. narrowing of resilience window, increasing vulnerability to additive stress and illness.
What are common CV pathophysiologies of aging
athetosclerosis
CAD
Essential HTN
CHF
Cardiac arrhythmias
Aortic Stenosis
What is the most frequent valvular heart disease
mitral stenosis
followed by Aortic Stenosis
What is the first line treatment for AF and VTE
DOACs
What are the types of comorbidities
coincidental
intercurrent
sharing common pathways
complicating
what is a coincidental comorbidity
coexisting chronic condition with unrelated pathogenesis
What is intercurrent comorbidities
acute illness such as URI which may mainfest with more severe symptoms in patients wiht chronic disease, or which may require different treatments
Whatare sharing common pathway comorbidities
common pathophysiology, such as IHD and Lung cancer can both be two seperate disease processes, both related to smoking
How do we measure kidney function in older adults
Serum Creatinine level
Creatinine clearance
GFR
What are common hematologic pathophysiology related to increasing age
anemia
leukemia
lymphoma
plasma cell disoders
what are symptoms that should not be overlooked in older patients
dyspnea
falls
LOCs
chest pain
dizziness
confusion
fatigue
depression*