Physio L1 Flashcards
Basic electrical rhythm and spike potential regulates what?
GIT motility only
Submucosal (Meissner’s) plexus regulates…
Secretion and control of blood flow
Myenteric (Auerbach’s) plexus controls…
The motility of GIT
Which type of reflex controls the normal secretion and motility (peristalsis) of the GIT ?
Local enteric reflex
Which type of GIT reflex is transmitted to the prevertebral sympathetic ganglia then back to GIT?
Intermediate (ganglionic) reflexes like entero-gastric, gastro-colic or colono-lieal relexes
Vago-vagal reflex is which type of GIT reflex
Long (Central) reflex
Which long reflex is an inborn reflex?
Unconditioned GIT reflex, such as presence of food in the mouth
What is the difference in brain centre between unconditioned and conditioned reflexes ?
Unconditioned: brain stem and pons
Conditioned: Cerebral cortex
What is Basic electrical rhythm?
Partial depolarization and repolarization made by interstitial cells of Cajal (pacemaker)
What ion is responsible for BER
Sodium influx into cajal cells which in turn transmitted by gap junctions
What factors can affect spike potentials?
Stretch, neuronal and hormonal (epinephrine), GIT hormones
The APUD cells act mainly by
Paracrine but also endocrine and neurocrine
Classify and enumerate the types of GIT hormones
Gastrins: gastrin and cholecystokinin (CCK)
Secretins: secretin, glucagon, glucose-dependent insulinotropic peptide (GIP)
Others: somatostatin and motilin
HSCR disease (congenital aganglionic megacolon)?
No ganglion cells in Auerbach plexus mainly and/or Meissner’s
Location: terminal rectum and a segment of colon
Clinical presentation, diagnosis and treatment of HSCR disease
C/P: Blockage, failure to pass meconium in first 24 hrs, vomiting constipation.
Diagnosis: radiography, barium enema, rectal biopsy
Treatment: surgical removal of aganglionic segment
