Physio II lecture 5 Flashcards
What is refraction?
The bending of light waves at an angulated surface of transparent material-note that might striking a perpendicular surface continues on through without bending
What does the degree of every fraction, amount of bending, depend on?
The ratio of the two reflective indicates of the two transparent media and the degree of angulation between the interface in the entering wavefront of the light waves
What is the reflective index?
It is the ratio of the velocity of light and air to the velocity of light traveling in the substance ratio index of air equals 1.0
What is the refractive power
It is a measure of how much a lens bends light Waze. It measured in diopters
One diopter equals
1 m divided by the focal length of a lens
What is a focal point?
The point through which all parallel rays of light will pass after passing through each part of the lens
What is the focal length?
The distance from the center of the lens to the focal point
Compare the eye to a camera
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How does the iris of the iPhone’s and in a similar manner to the iris diaphragm of a camera?
It controls the amount of light entering the eye from darkness to light conditions
the depth of focus of the lens to increases
the pupillary diameter decreases
What is emmetropia?
A normal eye with regard to depth of focus, parallel light rays from distant objects are in sharp focus on the retina when the ciliary muscle is completely relaxed, all distant objects can be seen clearly
What is hyperopia?
farsightednessusually due to an eyeball that is too short or occasionally a lens system that is too weakall distant objects can be seen clearly
What is myopia?
nearsightednesswhen ciliary muscle is completely relaxed, light rays coming from distant objects are focused in front of the retinausually due to too long of an eyeball
What kinds of lenses would be used to correct hyperopia and myopia?
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What is visual acuity?
A measure of the resolving power of the eye
What is the avg diameter of a cone in the retina?
1.5 um
What is teh maximum visual acuity for two point sources of light?
1.5 to 2 mm
What will light form a distant point source normally create?
a spot with a diameter of about 11 um and a center that is brighter than the periphery
Where is aqueous humor formed?
The ciliary processes
What does teh ciliary apparatus consists of?
two opposing layers of epithelial cells with a space btw them. Na ions are actively transported inot this space and are accompanied by Cl and bicarbonate ions
Where do Cl and bicarbonate ions draw water via osmosis into?
The space and the aqueous solution is then passes into the anterior chamber
How does the flow of fluid occur?
Fluid flows from the anterior chamber into the canal of Schlemm and from there into aqueous veins in the sclera
What is used to measure the intraocular pressure?
a tonometer-normal pressure is 15 mm Hg
glacoma
A group of eye conditions that leads to damage to the optic nerve
Photosensitive pegments in rods:
Rhodopsin
photosensitive pigments in cones:
three different color pigments
What are these photosensitive pigments?
transmembrane conjugated proteins
Outer segment
site of light sensitive photochemicals
inner segment
contains organelles esp mitochondria
synaptic body
connects with horizontal and bipolar cells
What are the major functional segments of the rod and the cone?
outer segmentinner segmentnucleus synaptic body
Rhodopsin =
scotopsin + 11-cis retinal
Rhodopsin + light —>
scotopsin +all-trans retinal
What is 11 cis retinal converted to?
all trans retinal and dissociates from scotopsin
What is metarhodopsin II?
an intermediate in this pathway that excites electrical changes in the rods
Bathorhodopsin (nsec)—>
lumirhodopsin
lumirhodopsin—>
metarhodopsin I
metarhodopsin I–>
metarhodopsin II
Metarhodopsin II—>
scotopsin or all trans retinal
scotopsin to
rhodopsin
all trans retinal to
11 cis retinal via isomerase orall trans retinol (vit A)
11 cis retinal to
rhodopsin
11 cis retinol to
11 cis retinal
all trans retinol vitamin A isomerase to
11 cis retinol-requires isomerase and metabolic energy
What does excitation of the rod cause?
Increased negativity of the intrarod membrane potential =hyperpolarization
What does decomposition of rhodopsin cause
decreases rod membrane conductance for Na ions in the outer segment
What does decomposition of rhodopsin result in?
hyperpolarization of entire rod membrane