PHYSIO Flashcards

1
Q

Volume of blood

A

5 litres out of 45 l of fluids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is hematocrit

A

Volume percentage of RBCs in blood 45%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Why RBCs are more in men than in women?

A

The effect of androgens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The most abundant leukocyte

A

Neutrophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

PH of blood with changes

A

Normal range = 7.35 - 7.45
Lower =acidosis
Higher= alkalosis
Less than 6.8 and higher than 8 causes death because it affects the enzymes and denatures proteins and affect k+ hydrogen levels and CNS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Normal intracellular potassium percentage

A

98%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The more acidic ?

A

Venous blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Where plasma proteins are produced

A

Generally in liver except for gamma globulins in lymphocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Main plasma proteins

A

Albumin
Globulin
Fibrinogen
Prothrombin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Plasma proteins

A

as building blocks of cells and tissues. They function
as enzymes, hormones, antibodies and transporters, they contribute to plasma
osmolarity and acid-base balance, they serve as an energy source under limiting
conditions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Complete proteins

A

Poultry fish eggs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Incomplete proteins

A

Causes amino acids deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Volume of blood in heart

A

5%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Highest amount of blood in?

A

Veins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What raises blood volume

A

Sex, pregnancy, muscular exercise, altitude, adrenaline injection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What lowers blood volume

A

Posture, blood pressure

17
Q

Fetal life erythropoeisis

A

1 2 months by yolk sac
Then by liver and spleen
Then bone marrow and lymph nodes

18
Q

Post natal erythropoeisis

A

Bone marrow
In abnormal conditions liver and spleen
Confined to bones ( tibia ,femur,ribs, sternum, vertebrae and pelvis)

19
Q

Lifespan of erythrocyte

A

120 days

20
Q

In which stage haemoglobin isn’t produced

A

Mature red blood cell

21
Q

True or false The number of reticulocytes in peripheral blood is more than in bone marrow

A

False

22
Q

Vitamin b12 names

A

Extrinsic factor
Cyanocobalamin
Maturation factor

23
Q

What b12 deficiency affects

A

Mylein sheath
Neutrophils
Causes megaloblastic anemia (pernicious) hb synthesis stays normal
Mcv>100 ~150

24
Q

Causes of vitamin b12 deficiency

A

1-veganism
2- malabsorption …. gastric causes congenital lack of intrinsic factor or total or partial gastrectomy
Intestinal causes chronic tropical sprue , ileal resection

25
Q

Folic acid deficiency

A

Megaloblastic anemia
No effect on myelin sheath

26
Q

Causes of Folate deficiency

A
  1. Inadequate dietary intake
  2. Malabsorption: Celiac disease, jejunal resection, tropical sprue.
  3. Increased requirements: Pregnancy, premature infant, chronic hemolytic
    anemia.
27
Q

Definite effects of vitamin B12 or folate deficiency:

A
  1. Megaloblastic anemia.
  2. Macrocytosis of epithelial cell surface.
  3. Neuropathy (B12 deficiency only).
  4. Sterility in severe anemia.
  5. Rarely reversible melanin skin pigmentation.