physical, chemical, + biological properties of organic compounds

Question 1

What can functional groups effect?

Answer 1

1) acid/base properties
2) water solubility
3) lipid solubility
4) shape
5) stereochemistry
6) toxicity
7) side effects

Question 2

ADME

Answer 2

1) Absorption
2) Distribution
3) Metabolism
4) Excretion

Question 3

What is the pH of blood?

Answer 3

7.4

Question 4

What is the pH of the stomach?

Answer 4

2

Question 5

What is the pH of the duodenum?

Answer 5

4

Question 6

What is the pH of urine?

Answer 6

6

Question 7

Are alkanes saturated or unsaturated?

Answer 7

saturated

Question 8

Are alkenes saturated or unsaturated?

Answer 8

unsaturated

Question 9

Are alkanes/cycloalkanes soluble or insoluble in aqueous environments?

Answer 9

insoluble

Question 10

Are alkanes/cycloalkanes soluble or insoluble in non-aqueous environments?

Answer 10

soluble

Question 11

What reactions do alkanes/cycloalkanes undergo?

Answer 11

1) combustion

2) halogenation

Question 12

What is cyclopropane used for medicinally?

Answer 12

general anaesthetic

Question 13

What is liquid paraffin used for medicinally?

Answer 13

laxative

Question 14

What is paraffin used for medicinally?

Answer 14

moisture-resistant base for ointments + creams

Question 15

Are alkenes/cycloalkenes soluble or insoluble in aqueous environments?

Answer 15

no

Question 16

What reactions do alkenes/cycloalkenes undergo?

Answer 16

1) addition
2) oxidation
3) reduction
4) polymerisation

Question 17

aromatic

Answer 17

flat, conjugated cyclic hydrocarbon

Question 18

Huckles rule

Answer 18

for a cyclic compound to be aromatic it must have 4n + 2 pi electrons where n must be a whole number

Question 19

Are aromatic hydrocarbons soluble or insoluble in aqueous environments?

Answer 19

insoluble

Question 20

Are aromatic hydrocarbons more or less stable than alkenes?

Answer 20

more

Question 21

What reactions do aromatic hydrocarbons undergo?

Answer 21

substitution

Question 22

Why do alcohols + phenols act as weak acids in water?

Answer 22

electronegative oxygen is able to support a negative charge

Question 23

Are alcohols + phenols susceptible to fast/slow metabolism?

Answer 23

fast

Question 24

isoelectric point

Answer 24

pH at which amino acids exist as zwitterions