Physical changes in late adulthood and during death and dying Flashcards

1
Q

theories of aging

A
  1. Evolutionary
  2. mutation accumulation
  3. somatic mutation
  4. disposable soma
  5. antagonistic pleiotropy
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2
Q

aging as a result of

declining fitness

A

Evolutionary

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3
Q

single somatic cell accumulates multiple DNA
mutations, producing oncogenes that lead to cell
proliferation

A

somatic mutation

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4
Q

genes with dual antagonistic effects at the opposite

ends of the spectrum of age

A

antagonistic pleiotropy

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5
Q

a trade-off between resources related to
reproduction and those for somatic repair to
maintain function and survival

A

disposable soma

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6
Q

genetic mutation occurs with time

A

Mutation accumulation

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7
Q

what is hayflick limit

A

intrinsic limitation to cellular division

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8
Q

state of permanent arrest

A

Cellular senescence

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9
Q

reason why cells

physiologically senesce

A

Telomeric attrition

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