Photosensitivity

Question 1

photosensitizers has a MW of less than

Answer 1

500 daltons

Question 2

the action spectrum that prod phototoxicity is mostly ins what lightregion?

Answer 2

UVa and extend to visible light region (320-425nm)

Question 3

Phytophotodermatitis. ___ in many plants may cause a phototoxic reaction.

Answer 3

Furocoumarins.

Question 4

what component of oil of bergamot will produce phytophotodermatitis?

Answer 4

Bergapten.

Question 5

Dermatiris bullosa striata pratensis

Layman term for the dermatitis.

Answer 5

grass or meadow dermatitis

Question 6

most common form of photosensitivity

Answer 6

polymorphous light eruption.
5-20% of adult population.

Papular (erythematopapular) most common variant.

Question 7

A variant of PLE in boys 5–2 yo, after sun exposire on cold but sunny days. typical lesions are feouped small papules and papulovesicles and crusting.

Answer 7

juvenile spring eruption.

UVA is the enducing spectrum.

Question 8

Women/ men who is more sensitive to UVA; and which is for visble light

Answer 8

Women- Uva

Men- visible light

Question 9

tx for PLE.

Answer 9

Sunblock
topical tacrolimus ointment at night or 2x a day.
systemic steroid

syst hydroxychloroquine sulfate 200-400mg/day.

Question 10

variant of PLE most seen in native americans.

Answer 10

Actinic prurigo.
female:male 2:1 and 6:1

childhood, begin as small papules or papulovesicles tht ceust and become impetiginized. pruritc and excoriated.
Conjunctivitis in 10-20%
Cheilitis may be the only feature for years.
occur march through the summer and remit in the winter.

Question 11

Tx of actinic prurigo.

Answer 11

Thalidomide.

topical cyclosporine 2% controlling limbal lesions of actinic prurigo assoc conj.

Question 12

How many percent has a family history in Actinic prurigo?

Answer 12

75%
in europe 80% occur before age 10.
US, 45% before age 10, 72% before 20 yo.