Phenytoin Flashcards
Should you use injectable phenytoin
No - risk of severe harm and error
What route should you take
IV
What vitamin should you use with it
Vitamin D
Range of phenytoin
10-20 (everyone older than 3 months)
6-15 (under 3 months)
What are the three signs of toxicity
Nystagmus, rash, blood and skin disorders
What electrolyte imbalance can phenytoin cause
Hyperkalemia
Is it an enzyme inducer or inhibitor
Inducer so decreases concs of Doacs, Bupropion, Buspirone, Carbamezapine, Ciclosporin, COC, valproate
Phenytoin and miconazole
Increases phenytoin toxicity
Amiodarone and phenytoin
Increases conc of phenytoin
Side effects of phenytoin
P-45 inducer
Hirutism
Enlarged gums
NYstagamus
Teratogenic
Osteopenia
Interferes with folic acid
Neuropathy