Digoxin

Question 1

What is the range for digoxin

Answer 1

1 to 2

Question 2

Pneumonic for key info

Answer 2

2 (Dont go over this range)
K (Potassium - low- can cause Digoxin toxicity
I Increases force and contraction of heart
D Diarrhoea, nausea and vomiting
N Nausea and Vomiting
E -
Y Yellow vision
S Need potassium SPARING diuretic because if potassium is spared then you wont suffer low potassium

Question 3

Maintenance dose for AF

Answer 3

125 to 250 mcg - loading dose required too

Question 4

Worsening or severe HF

Answer 4

62.5mcg to 125mcg OD - no loading dose required

Question 5

Signs of digoxin toxicity

Answer 5

Yellow vision
Diarrhoea
Arrythmias

Question 6

When is digoxin concentration taken

Answer 6

6 hours after a dose

Question 7

What electrolytes are measured

Answer 7

Potassium (low levels can cause hypokalemia)
Magnesium (hypo can cause toxicity)
Calcium (high levels cause toxicity)
Oxygen (hypoxia can cause toxicty)

Question 8

Interactions of digoxin

Answer 8

C CCB (increases levels)
R Rifampicin (decrease levels)
A Amidarone (increases levels)
S St. Johns Wart (increases levels)
E Erythromycin (increase concentration)
D Diuretics (decrease potassium)