phenylalklyamines Flashcards
name the different phenylethylamine alkaloids
natural:
ephedrine
mescaline
cathine/cathinone
buproprion
synthetic
amphetmine
salbutamol
categorize phenylethylamine alkaloids into their effects
neurotransmitters
stimulants (ephedrine , amphetmine , cathinone)
bronchodilators (salbutamol and ephedrine)
antidepressants (bupropion)
hallucinogens (mescaline)
what is cathinone a constituent of
Catha edulis
what is colloquially known as speed
amphetmine
what is the reduced form of cathinone
cathine aka norpseudoephdrine
what is the source of mescaline
from the cactus lophophora williamsii
what is the source of ephedrine
ephedrine is found in different species of the genus Ephedra the family is Ephedracaea
ex - Ephedra sinica (E. sinica) ; E. vulgaris ; E. equestina
alkaloids present in the different species of the genus Ephedra
(-) ephedrine (levo)
N-methyl ephedrine
nor pseudoephedrine aka cathine
pseudoephedrine
what is the antidepressant phenylethylamine alkaloid called and what does it resemble
bupropion aka wellbutrin
it looks like cathinone
what is the parent compound of phenyalkylamines and what is imp to know abt it and how is it formed
phenylethylamine and its not found in nature but its deriviteves are found in nature
it biosynthesized from phenylalanine via enzymatic decarboxyaltion
uses of ephedrine and what salts its used as
sympathomimetic agent
bronchodilator
Nasal decongestant
pressor bc it increases BP
CNS stimulant
used as ephedrine HCl (BP) or ephedrine sulfate (USP)
whats the similarity and difference between ephedrine and adrenaline
they both have similar structures and effects and are the link to animal and plant kingdom
adrenaline is more potent than ephedrine but ephedrine is orally active and has a longer DOA
