Phase 2 - Resp

Question 1

Common microbial colonisers of airways in Cystic Fibrosis

Answer 1

• S Aureus- H Influenzae- Klebsiella pneumoniae- E coli- Burkhodheria cepacia- PSEUDOMONAS AERUGINOSA (particularlly hard to treat - can become resistant to multiple antibiotics) - the reason it is now discouraged to have group meet ups for children with cystic fibrosis

Question 2

Treatment of pseudomonas colonisation in airways

Answer 2

• Nebulised Tobramycin- Oral ciprofluxacin

Question 3

Causes of Type 2 resp failure

Answer 3

• Airways obstruction (COPD, v severe Asthma)- Alveolar hypoventilation - Emphysema - Obesity (e.g. in sleep apnea) - Reduced resp drive (e.g. on opiates) - Muscular weakness (MND)