Pharmocology Unit 5

Question 1

brompheniramine

Answer 1

H1 antihistamine; OTC for allergy, hay fever; analog of diphenhydramine

Question 2

chlorpheniramine

Answer 2

H1 antihistamine; OTC for allergy, hay fever; analog of diphenhydramine

Question 3

clemastine

Answer 3

H1 antihistamine; OTC for allergy, hay fever; analog of diphenhydramine

Question 4

dextromethorphan

Answer 4

antitussive; OTC for sough (NyQuil); not well absorbed, not addictive; cold prep

Question 5

oxymetazoline

Answer 5

alpha agonist, phenylephrine derivative; OTC fornasal congestion; cold prep

Question 6

xylometazoline

Answer 6

alpha agonist, phenylephrine derivative; OTC fornasal congestion; cold prep

Question 7

guaifenesin

Answer 7

expectorant; OTC to remove mucus plugs (robitussin); cold prep

Question 8

polymyxin

Answer 8

OTC abx for topical first aid/wound care

Question 9

tolnaftate

Answer 9

OTC antifungel for athletes foot/skin infections (tinactin)

Question 10

benzoyl peroxide

Answer 10

OTC antimicrobial for acne vulgaris; was category III -> moved to category I

Question 11

meclizine

Answer 11

OTC antiemetic to prevent/treat motion sickness; 2nd gen antihistamine (reduces sedation effects)

Question 12

doxylamine

Answer 12

OTC for insomnia; H1 antihistamine

Question 13

naphazoline

Answer 13

OTC alpha agonist for red/bloodshot eyes

Question 14

tetrahydrozoline

Answer 14

OTC alpha agonist for red/bloodshot eyes

Question 15

orlistat

Answer 15

OTC weight loss drug for treatment of obesity; binds to and prevents fat absorption

Question 16

B vit complex

Answer 16

energy

Question 17

folate

Answer 17

neural tube defects

Question 18

vitamin A

Answer 18

beta-carotene; vision, skin

Question 19

vitamin D

Answer 19

osteoporosis, hypocalcemia

Question 20

vitamin C

Answer 20

colds?

Question 21

vitamin E

Answer 21

aging?

Question 22

calcium

Answer 22

fractures, osteoporosis

Question 23

potassium

Answer 23

hypertension (diuretics, heart)

Question 24

magnesium

Answer 24

heart/circulation

Question 25

iron

Answer 25

anemia

Question 26

chromium

Answer 26

blood sugar/diabetes?

Question 27

zinc

Answer 27

colds/immune fxn?

Question 28

olive oil

Answer 28

prevent heart disease

Question 29

amino acids

Answer 29

in energy drinks for energy

Question 30

oat bran

Answer 30

decr cholesterol

Question 31

soy products

Answer 31

prevent heart disease, osteoporosis

Question 32

melatonin

Answer 32

sleep aid

Question 33

glucosamine and chondroitin sulfates

Answer 33

osteoarthritis

Question 34

androstenedione

Answer 34

incr strength

Question 35

DHEA

Answer 35

prevent aging?

Question 36

CoQ10

Answer 36

antioxidant - aging?

Question 37

green tea

Answer 37

antioxidant - polyphenol EGCG

Question 38

garlic

Answer 38

antioxidant - allicin (also lowers cholesterol?)

Question 39

milk thistle

Answer 39

antioxidant - silybin

Question 40

echinacea

Answer 40

immunomodulator - cold flu?

Question 41

ginkgo biloba

Answer 41

?? memroy loss, arterial disease, vertigo, and tinnitus; direct antiplatelet activity

Question 42

ginger

Answer 42

?? upset stomach and stimulant??; direct antiplatelet activity

Question 43

ginseng

Answer 43

ginsenosides - libido, fatigue; direct antiplatelet activity

Question 44

guarana

Answer 44

stimulant - caffeine; also antioxidant

Question 45

kava

Answer 45

sedative - kavalactone; GABA, MAO-B

Question 46

licorice

Answer 46

isoflavones - expexctorant, endocrine modulator; can have sympathomimetic effects -> limited use in hypertension

Question 47

ma huang

Answer 47

stimulant - ephedra; asthma, wt reduction; sympathomimetic; banned by FDA for drug-related deaths in 2004&6

Question 48

saw palmetto

Answer 48

phytosterols - benign prostatic hypertrophy

Question 49

St John's Wort

Answer 49

??? anxiety and depression; reuptake inhibitor and MAOI-like properties -> can enhance efficacy of anti-depressants

Question 50

valerian

Answer 50

sedative - valproic-like compund; GABA

Question 51

albendazole

Answer 51

antihelminth

Question 52

mebendazole

Answer 52

antihemlminth

Question 53

ivermectin

Answer 53

antihelminth

Question 54

artemether-lumefantrine

Answer 54

anti-malarial

Question 55

malarone (ATOVAQUONE-PROGUANIL)

Answer 55

anti-malarial

Question 56

chloroquine

Answer 56

anti-malarial

Question 57

mefloquine

Answer 57

anti-malarial

Question 58

metronidazole

Answer 58

anti-protozoal

Question 59

nitazoxanide

Answer 59

anti-protozoal