Pharmacy Practice and Administration

Question 1

MOA: Binds to estrogen receptors and suppress LH

Answer 1

Black cohosh

*can cause miscarriage

Question 2

Most effective served hot

Answer 2

Echinacea

Question 3

Used for Menopausal symptoms

Answer 3

Black cohosh

Question 4

Proanthocynidins may inhibit E.Coli from adhering site in the Urinary Tract thus limiting the ability of the bacteria to spread

Answer 4

Cranberry

Question 5

MOA: unknown possibly due to up regulation of TNF-alpha messenger RNA (alkamides) or anti-inflammatory actions

Answer 5

Echinacea

Question 6

Used in Airborne to Tx common cold

Answer 6

Echinacea

Question 7

Flavonoid complex- silymarin extracted from seeds. shown to suppress cell growth and anti-cancer effects

Answer 7

Milk thistle

Question 8

Tx gallbladder and lever complaints

Answer 8

Milk thistle

Question 9

EPA and DHA and ADHD

Answer 9

Omega-3 fish oil

Question 10

Extract of hypericum perforatum flower

Answer 10

St. John’s Wort

Question 11

Similar effects as SSRIs

Answer 11

St. John’s Wort

Question 12

Tx for mild to moderate depression, anxiety, pain

Answer 12

St. John’s Wort

Question 13

Pharmacodynamics: What is the receptor sensitivity to Benzodiazepines, warfarin, opioids?

Answer 13

Increased

Question 14

Pharmacodynamics: What is the sensitivity to beta-blockers?

Answer 14

Decreased

Question 15

Pharmacodynamics: What is the sensitivity to Baroreceptors?

Answer 15

Decreased; risk of orthostatic hypotension

Question 16

Pharmacodynamics: What is the sensitivity to vasodilators, TCA, anithypertensives?

Answer 16

Decreased baroreceptor sensitivity; risk of orthostatic hypotension

Question 17

Pharmacodynamics: Increased risk of Tardive Dyskinesia and pseudoparkinsonism with which agents?

Answer 17

Antipsychotics

Question 18

Pharmacodynamics: Hypokalemia

Answer 18

increased digoxin toxicity

Question 19

Pharmacodynamics: Hyperkalemia

Answer 19

NSAIDS, ACEi, K+-sparing

Question 20

Orthostatic hypotension, sedation, extrapyramidal effect

Answer 20

Antipsychotics

Question 21

Don’t combine with sulfa drugs, macrolides, quinolones

Answer 21

Warfarin

Question 22

Don’t combine with ACE inhibitors

Answer 22

Spironolactone

Question 23

Don’t combine with Digoxin

Answer 23

Amiodorone

Question 24

Don’t use more than 7Xs per week, or twice per occasion, or with any medications

Answer 24

ETOH

Question 25

A in Armor

Answer 25

Access the disease state

Question 26

R in Armor

Answer 26

Review the current meds profile

Question 27

Can be used to Tx both HTN and angina

Answer 27

CaChannel blockers or Beta blockers

Question 28

Can be used to Tx both HTN, HF, and renal protection for diabetics

Answer 28

ACE inhibitors

Question 29

Can be used to Tx both HTN and prostate

Answer 29

Alpha-blocker

Question 30

Overdose is N/V dizziness, nervous system and visual disturbances, reduced HR, increased RR

Answer 30

Black Cohosh

Question 31

Can cause urinary stones from oxalate in tablets

Answer 31

Cranberry

Question 32

Taken as a tea. Don't take if plant allergies

Answer 32

Echinacea

Question 33

MOA: Allicin reduced activity of the thiol group found in some enzymes such as CoA and HMG-CoA which are factors in lipid synthesis

Answer 33

Garlic

Question 34

N/V, BLEEDING RISK, heartburn, bad breath, body odor

Answer 34

Garlic

Question 35

MOA: contains flavonoids and terpenoids which improve blood flow and antioxidant

Answer 35

Ginkgo

Question 36

Can be a strong allergen. Used for memory, asthma, anxiety, claudication, tinnutis and vertigo

Answer 36

Ginkgo

Question 37

ASA and Coumadin interaction - increases bleeding risk

Answer 37

Ginkgo

Question 38

Antidepressant interaction - increased side effects risk

Answer 38

Ginkgo

Question 39

Monitor for increased bruising or bleeding especially with ASA or PLAVIX

Answer 39

Fish Oil

Question 40

Berries only for men

Answer 40

Saw Palmetto

Question 41

MOA: Inhibits 5 alpha reductase. Reduces conversion of testosterone to DHT. SEs = HA, GI

Answer 41

Saw Palmetto

Question 42

Pea Plant, Isoflavones and phytoestrogens

Answer 42

Soy

Question 43

MOA: 5HT, dopa, NE reuptake inhibition. Possible antagonism of BZD, GABA receptor SEs: Paresthesias, HA, Nausea, withdraw same as SSRIs

Answer 43

St. John's Wort

Question 44

A1C if older than 65 and newly Dz Diabetes

Answer 44

7-7.5

Question 45

A1C if older than 65 and comorbid and sick and may die soon

Answer 45

8-9

Question 46

A1C for most adults over 65. Includes 3 comorbidities

Answer 46

7.5-8