Pharmacovigilance in the hospital setting: Safe prescribing Flashcards
what is a medication error?
A medication error is any preventable event that may cause or lead to inappropriate medication use or patient harm while the medication is in the control of the health care professional, patient, or consumer. Such events may be related to:
professional practice
health care products
procedures and systems
product labeling, packaging, and nomenclature
dispensing
distribution
administration
education
monitoring
Which patients are most at risk from medication errors?
Those undergoing cardiothoracic surgery, vascular surgery, or neurosurgery
Those with complex conditions
Those in the emergency room
Those looked after by inexperienced doctors
Older patients
Top ten prescribing errors
- Prescriptions for medicines were omitted or delayed e.g. discharge meds, antibiotics
- Anticoagulants e.g. warfarin
- Opioid analgesics
- Insulin
- Nonsteroidal anti-inflammatory drugs
- Drugs that require regular blood test monitoring e.g. digoxin, diuretics, antiepileptics
- Known allergy to medicine, including antibiotics
- Drug interactions
- Loading doses e.g amiodarone, warfarin
- Oxygen therapy
People related causes of medication incidents
Fatigue: Sleep deprivation
Hunger: Long lapses between food/drink
Concentration: Lapses
Stress: Loss of control/cutting corners
Distraction
Lack of training
Lack of access to information (not timely)
Other factors: Alcohol, drugs & illness
Common Prescribing Errors
Wrong drug (e.g. drugs that sound alike)
Wrong dose
Inappropriate Units
Poor/illegible prescriptions
Failure to take account of drug interactions
Omission
Wrong route/multiple routes (IV/SC?PO)
Calculation errors (important in Paediatrics)
Poor cross referencing
Infusions with not enough details of diluent, rate etc. Poor cross-referencing between charts
Once weekly drugs
Multiple dose changes
Illegible Handwriting: Error Prevention
Prescribers’ Obligation
Write/Print more carefully
Computers
Verbal communication
Avoid decimal points if possible
Never leave a decimal point ‘naked’
Never use a terminal zero
Leave a space between name and dose
The Five R’s
Right Patient
Right Drug
Right Dose
Right Route
Right Time
National formularies
(e.g. the BNF)
provide an independent source of advice
Grampian joint formulary
reflects hospital/primary care choices
WHO
provide a ‘model’ list of essential drugs (~300 items); some controversial!