Pharmacovigilance + EBPH + Homelessness Flashcards
1
Q
Pharmacovigilance in action
A
- Detection
- Assessment
- Understanding - e.g. QT risks in elderly
- Prevention - avoid ADRs where possibly
2
Q
What is an adverse event?
A
Undesired patient outcome while patient is taking a medicine but may not necessarily be caused by that medicine
Therefore all ADRs are AEs but not vice versa
3
Q
Effects of ADRs?
A
mimic disease, affect quality of life
affect compliance
reduce patient’s confidence in HCPs
reduce available choice of drug treatment
4
Q
Post marketing surveillance duration
A
extensive for at least 5 years after release
5
Q
Methods of PMS
A
- voluntary (SRS)
- prescription event montitoring
- medical record linkage
6
Q
Yellow card
A
unreliable for rate of side effects
effective for immediate ADRs
7
Q
CHIMES
A
Child Medical Record for Safer Medicines
8
Q
DoTS 3 part system
A
- Dose-related
- Time-related
- Susceptibility - e.g. elderly, paeds, ethnicity, genetics, metabolism
