Pharmacology--specific antidotes Flashcards by Julia Newman

Q

Acetaminophen

A

N-acetylcysteine (replenishes glutathione)

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Q

AChE inhibitors, organophosphates

A

Atropine > Pralidoxime

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Q

Amphetamines (basic)

A

NH4Cl (acidify urine)

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Q

Antimuscarinic, anticholinergic agents

A

Physostigmine salicylate, control hyperthermia

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Q

Benzodiazepines

A

Flumazenil

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Q

Beta blockers

A

Glucagon

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Q

Carbon monoxide

A

100% O2, hyperbaric O2

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Q

Copper, arsenic, gold

A

Penicillamine

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Q

Cyanide

A

Nitrite + thiosulfate, hydroxocobalamin

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Q

Digitalis (digoxin)

A

Anti-dig Fab fragments

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Q

Heparin

A

protamine sulfate

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Q

Iron

A

Deferoxamine, deferasirox

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Q

Lead

A

EDTA, dimercaprol, succimer, penicillamine

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Q

Mercury, arsenic, gold

A

Dimercaprol (BAL), succimer

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Q

Methemoglobin

A

Methylene blue, vitamin C

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Q

Opioids

A

Naloxone, naltrexone

Q

Salicylates

A

NaHCO3 (alkalinize urine), dialysis

Q

TCAs

A

NaHCO3 (plasma alkalinization)

Q

tPA, streptokinase, urokinase

A

Aminocaproic acid

Q

Warfarin

A

Vitamin K (delayed effect), fresh frozen plasma (immediate)