Pharmacology Orientation and Scope Flashcards
Substance that brings about a change in biologic fx through is chemical action
Drug
Their role is to ensure drugs are proven safe and effective
FDA
This is converted to the active drug by biologic processes inside the body
Pro-drug
Field of study of the appropriate use of medications to effectively treat of prevent disease and manage symptoms
Pharmacotherapeutics
Field of study of genetic impact on drug metabolic or handling processes which can affect individual responses to drugs
Pharmacogenomics
Field of study utilizing scientific and economic methods to evaluate and compare value between therapies
Pharmacoeconomics
Field of study that applies epidemiological principles and methods to study the uses and effects of medications on large populations
Pharmacoepidemiology
For drugs to be considered pharmaceutically equivalent they must have what similar characteristics?
Same ingredients
Same dosage form/route
Same strength/concentration
Same standards for for quality/purity
What is the difference between therapeutic equivalence and bioequivalence?
Therapeutic: drugs must be pharmaceutically equivalent and have the same therapeutic/clinical effects and safety profile
Bioequivalence: similar rate and extent of absorption
What are A codes vs B codes when talking about the FDA code letter rating system for therapeutic equivalence?
A codes: drugs that are considered to be therapeutically equivalent to other pharmaceutically equivalent products
B codes: drugs that are NOT considered to be therapeutically equivalent to other pharmaceutically equivalent products
Mg= \_\_\_g Mcg= \_\_\_ mg mEq= \_\_\_ Eq Kg= \_\_\_ lbs
Tsp= \_\_\_ ml Tbsp= \_\_\_ ml Oz= \_\_\_ ml Ml/cc= \_\_\_ L Quart= \_\_\_\_ ml Pint= \_\_\_ ml Liter= \_\_\_\_ ml Gallon= \_\_\_\_ L
1/1000
1/1000
1/1000
2.2
5 15 30 1/1000 946 473 1000 3.79
Meds are designated into what two groups?
- Over the counter with no prescription
- Legend with prescription required: scheduled/controlled based on abuse potential/dose
Non-scheduled/non-controlled with no abuse potential
What is schedule 1 criteria?
Examples?
Drugs with no currently accepted medical use and a high potential for abuse. Most dangerous with psychological or physical dependence
Heroin LSD Marijuana Ecstasy Methaqualone Peyote
What is schedule 2 criteria?
Examples?
Drugs with a high potential for abuse leading to psychological or physical dependence
Vicodin (< 15 mg of hydrocodone) Cocaine Methamphetamine Methadone Dilaudid Demerol Oxycodone Fentanyl Dexedrine Adderall Ritalin
What is schedule 3 criteria?
Examples?
Drugs with moderate to low potential for physical and psychological dependence
Tylenol Codeine Ketamine Anabolic steroids Testosterone