Pharmacology medications Flashcards
What is drug target interaction?
It is the way a drug interacts with the drug target (the molecule) to produce a biological effect.
What is a drug target?
It is a molecule (often protein) in which a drug can be produced to have a biological effect on.
Agonist
Endogenous (molecule like a hormone made in the body) or exogenous (molecule of drug) molecules that elicit a biological response.
Antagonist
Molecules that bind to a receptor to limit the effect of agonists but lack an effect of their own.
Mechanism of drug action
the process by which a drug produces a biological effect.
Name 3 antihistamine drugs
Loratadine, Chlorphenamine, Cetrizine
Name the class, drug target, drug target interaction and mechanism of drug action of 3 antihistamines
Loratadine, Chlorphenamine, Cetirizine. They are antihistamines. They are H1 receptor antagonist, and they block the H1 receptor.
Name the class, drug target, drug target interaction and mechanism of drug action of Lidocaine
It is a local anesthetic, it acts on voltage gated Na+ channels, they are competitive inhibitors that block the Na+ channels.
Name the class, drug target, drug target interaction and mechanism of drug action of Morphine and Naloxone
Naloxone - It is an opiate antagonist. it blocks opioid receptor. It is an antagonist.
Morphine - It is an opiate. it acts on delta, kappa and mu opioids, it is an agonist, and it ca
Understand how bacteria characteristics influence the choice of antibiotic.
Understand the selection of an antibiotic
Describe the categories of anti-bacterial agents
Explain the main mechanisms of action of each category of antibiotic and how selective toxicity is achieved (or not)
Describe associated adverse effects
Understand the importance and main mechanisms of antibacterial resistance
