Pharmacology II

Question 1

It is based on the structure of a common soil mold.

Answer 1

Tetracyclines

Question 2

What is the drug action of tetracyclines?

Answer 2

inhibits protein synthesis

Question 3

What are the four types of tetracyclines?

Answer 3

Tetracycline
Demeclocycline
Doxycycline
Minocycline

Question 4

Is toxic to humans in high concentrations

Answer 4

Tetracyclines

Question 5

Contraindications of Tetracyclines

Answer 5

Should not be given to 8yrs old and below related to enamel damage
PTs with renal and hepatic dysfunction
PTs with fungal, mycobacterial, viral ocular infections

Question 6

Adverse effects of Tetracyclines related to GI

Answer 6

N/V
Diarrhea
Abdominal Pain
Glossitis
Dysphagia

Question 6

Dermatological adverse Effect of Tetracyclines

Answer 6

Photosensitivity
Rash

Question 7

Hematological adverse effect of Tetracyclines

Answer 7

Hemolytic Anemia
Bone Marrow Depression

Question 8

Other Adverse Effect of Tetracyclines

Answer 8

Intracranial Hypertension
Fatal Hepatoxicity

Question 8

group of bacteria that contain the pathogen that cause tuberculosis and leprosy

Answer 8

Mycobacteria

Question 9

Specific bacteria that causes Tuberculosis

Answer 9

Mycobaterium Tuberculosis

Question 10

Specific bacteria that causes Leprosy

Answer 10

Mycobaterium Leprae

Question 11

Other term for Leprosy

Answer 11

Hansen’s Disease

Question 12

a disfiguring skin lesions and destructive effects on reparatory tract.

Answer 12

Leprosy

Question 13

1st line drugs for Tuberculosis

Answer 13

Isoniazid (INH)
Rifampin
Rifapentine
Ethambutol
Pyrazinamide
Streptomycin

Question 14

2nd line of drugs for Tuberculosis

Answer 14

Capreomycin
Cycloserine
Ethionamide
Rifabutin

Question 15

other drugs effective for 2nd line of drugs for tuberculosis

Answer 15

Kanamycin
Ciprofloxacin
Levofloxacin
Ofloxacin

Question 16

Drug that treats leprosy

Answer 16

dapsone

Question 17

a hypnotic drug that is given to PTs after leprosy treatment that helps with sleep and decreases stress

Answer 17

Thalidomide

Question 18

C/I with Mycobacterial Drugs

Answer 18

Known Allergy to agents
Renal and Hepatic Failure

Question 19

CNS effects with Mycobacterial Drugs

Answer 19

Neuritis
dizziness
headache
malaise
drowsiness
hallucinations

Question 20

GI tract effects with Mycobacterial Drugs

Answer 20

N/V
Anorexia
Stomach Upset
Abdominal Pain

Question 21

What are the drugs that if paired with Mycobacterial drugs could lead to toxic liver reactions

Answer 21

Quinidine
metoprolol
propranolol
corticosteroids
oral contraceptives
oral anticoagulants
oral anti-diabetic agents
digoxin
thephylline
methadone
phenytoin
verapramil
cyclosporin
ketoconazole

Question 22

What are the different Macrolide drugs?

Answer 22

Erythromycin
Azithromycin
Clarithromycin
Dirithromycin

Question 23

What are the bacteria that is being treated with Macrolides?

Answer 23

Streptococcus pneumoniae mycoplasma pneumoniae Listeria monocytogenes Legionella pneumophilia group A beta-hemolytic streptococci Neisseria gonorrhoeae Haemophilus influenzae Corynebacterium diptheriae corynebactrium minutissimum

Question 24

C/I and cautions with macrolides

Answer 24

Allergies Hepatic Dysfunctions Lactating and Pregnant Women

Question 25

GI tract effects with macrolides

Answer 25

abdominal cramps anorexia diarrhea vomiting colitis

Question 26

Neurological Symptoms with macrolides

Answer 26

confusion abnormal thinking uncontrollable emotions

Question 27

Drugs under Lincosamides

Answer 27

Clindamycin Lincomycin

Question 28

Monobactam Antibiotics

Answer 28

Aztreonam

Question 29

is effective to treat patients who are allergic to penicillin and cephalosphorin

Answer 29

Aztreonam

Question 30

The only approved drug under ketolids

Answer 30

Telthromycin

Question 31

Hypersensitivity Reactions with Ketolids

Answer 31

congenital prolonged QT interval bradycardia hypokalemia cardiac antiarrhythmics

Question 32

Telthromycin should not be paired with

Answer 32

pimozide, simvastatin atorvastatin lovastatin

Question 33

Could cause increased serum levels if Ketolids be paired with

Answer 33

digoxin and metoprolol

Question 34

Decreased serum levels when ketolids be paired with

Answer 34

rifampin phenytoin, carbamazepine phenobarbital

Question 35

New Antibiotics are

Answer 35

Daptomycin Linezolid Tigecycline Quinupristin Dalfopristin Fidaxomicin

Question 36

Is a combination of Quinupristin and Dalfopristin

Answer 36

Streptogramins

Question 37

a new antiobiotic similar to rifampin

Answer 37

Rifaximin