Pharmacology-Drugs

Question 1

Cox inhibitor mild-mod pain

non-opiod analgesis fever

antipyretic

**acetaminophen **

hepatotoxicity warfarin

renal failure

Answer 1

hepatotoxicity-dark urine, clay colored stools, yellow skin, sclera, itching, abdominal pain, fever, diarrhea

allergic reactions: rash, uritcararia

Question 2

mucolytic acetaminophen toxicity

                                                             bronchitis, CF, COPD                       

atelectasis

acetylcysteine

(Mucomyst)

hepatotoxicity Fe, Cu, Ni

bronchospasm, hemoptysis

anaphylaxis, andioedema

Question 3

anti-anxiety anxiety, panic disorders

benzodiazepine

alprazolam

(Xanax)

ECG changes, tachycardia CNS depressants

dizziness, drowsiness grapefruit juice

headache, dry mouth digoxin

nausea, constipation

Answer 3

contra/precautions: renal or hepatic dysfunction, acute angel-closure glaucoma

nursing: physiologic dependence

Question 4

CNS stimulant ADHD

                                                                        narcolepsy

amphetamine sulfate

(Adderall)

irritability, restlessness i.e. of adrenergics

nervousness, anxiety, i.t.:CNS stimulants,

headache, insomnia, dry mouth digoxin MAOI’s

anorexia tricyclic antidepressants

Answer 4

contra/precautions: hypertension, CV disease, anxiety, agitation, glaucoma, psychopathologic disorders, hyperthyroidism, Tourette’s, suicidal/homicidal

tolerance, psychologic dependence

Schedule II

Question 5

psychotherapeutic ADHD

atomoxetine

(Strattera)

suidicidal thinking/behavior

Answer 5

not addictive (not an amphetamine)

Question 6

psychomotor stimulant ADHD

release: serotonin, dopamine, narcolepsy

norepinephrine

methylphenidate

(Ritalin, Concerta)

irritability, restlessness i.e. of adrenergics

nervousness, anxiety, i.t.:CNS stimulants,

headache, insomnia, dry mouth digoxin MAOI’s

anorexia tricyclic antidepressants

Question 7

antidysrhythmic bradycardia

anticholinergic reversal of anticholinesterase agents

parasympatholytic insecticide poisoning

antimuscarinic blocking vagal cardiac reflexes

                                        decreasing secretions bf surgery

                                                   antidote for cholinergic OD

atropine

incr HR, dysrhythmias additive: antihistamines

CNS excitation, tricyclic antidepressants

restlessnes amantadine

Answer 7

cholinergic blocker–blocks acetylcholine at parasympathetic neuroeffector sites, increases cardiac output, increases heart rate by blocking vagal stimulation in heart, dries sectretions by blocking vagus

blocking parrasympathetic nerves allows the sympathetic (adrenergic) nervous sytem to dominate. Cholinergic blockers = adrenergics

compete with aecetylcholine for binding at muscarinic receptors of PNS.