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ASNSW ICP STUDY > Pharmacology Adverse Effects > Flashcards

Pharmacology Adverse Effects Flashcards

1
Q

ADRENALINE - Adverse effects

A
  • Tachycardia
  • Dysrhythmias, including ventricular fibrillation
  • Hypertension
  • Pupillary dilation
  • Anxiety
  • Nausea and vomiting
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2
Q

AMIODARONE – adverse effects

A
  • Hypotension
  • bradycardia
  • dysrhythmias
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3
Q

ASPIRIN - Adverse Effects

A
  • Allergic reactions, e.g. asthma, angioneurotic oedema, rhinitis, urticaria, laryngeal oedema and shock. Always check for history of previous reaction
  • Aggravation of any bleeding tendency
  • Gastric irritation (unlikely to be significant with one tablet)
  • Bleeding may take longer to stop
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3
Q

ATROPINE - Adverse effects

A
  • Dry mouth
  • Blurred vision
  • Tachycardia
  • Nausea and vomiting
  • Hyperthermia
  • Dysrhythmias
  • Agitation, delirium, hallucinations, seizure and coma may occur in high doses
  • Urinary retention
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4
Q

CALCIUM GLUCONATE – adverse effects

A
  • May increase myocardial and cerebral damage by increasing intracellular calcium levels
  • Tissue necrosis if extra visitation from vain occurs
  • Dysrhythmias
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5
Q

FENTANYL - Adverse Effects

A
  • Respiratory depression
  • Hypotension
  • Nausea and vomiting
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6
Q

FEXOFENADINE - Adverse Effects

A
  • Headache
  • Drowsiness
  • Nausea
  • Dry mouth
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7
Q

FRUSEMIDE - Adverse Effects

A
  • Excessive diuresis can lead to hypovolaemic shock
  • Potassium loss can precipitate dysrhythmias
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8
Q

GLUCAGON - Adverse Effects

A
  • Nausea and vomiting
  • Allergic reactions rarely occur
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9
Q

GLUCOSE 10% - Adverse Effects

A
  • Tissue necrosis if extravasation from vein occurs
  • May aggravate brain damage in head injuries and strokes
  • May precipitate Wernicke’s encephalopathy in alcoholics with thiamine deficiency
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11
Q

GLUCOSE GEL - Adverse Effects

A

May precipitate Wernicke’s encephalopathy in alcoholics with thiamine deficiency

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11
Q

GLYCERYLTRINITRATE - Adverse Effects

A
  • Hypotension
  • Flushing
  • Headache
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13
Q

HARTMANN’S - Adverse Effects

A
  • Cardiogenic pulmonary oedema
  • Coagulopathy, hypothermia and acidosis in the trauma patient
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14
Q

IPRATROPIUM BROMIDE - Adverse Effects

A

Mild anticholinergic effects, e.g. urine retention

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15
Q

Lignocaine – adverse effects

A
  • Lignocaine may cause or exacerbate ventricular dysrhythmias
  • In high doses, may cause:
    1. Neurological side effects - (drowsiness, disorientation, agitation, muscle twitching, fits and coma)
    2. Cardiac effects - (hypotension, bradycardia, heart block(s) and asystole)
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16
Q

METHOXYFLURANE - Adverse effects

A
  • ↓LOC
  • Renal damage in high doses
17
Q

METOCLOPRAMIDE - Adverse Effects

A
  • Restlessness, drowsiness and fatigue
  • Extrapyramidal / acute dystonic reactions including spasm of the facial muscles, trismus, rhythmic protrusion of the tongue, abnormal speech, spasm of the extra ocular muscles and unnatural positioning
18
Q

MIDAZOLAM - Adverse Effects

A

• ↓LOC resul

19
Q

MORPHINE - Adverse Effects

A
  • ↓LOC
  • Respiratory depression
  • Hypotension
  • Nausea and vomiting
20
Q

NALOXONE - Adverse Effects

A
  • Opioid withdrawal (nausea, vomiting, sweating, tachycardia, hypertension, combative behaviour)
  • Pulmonary oedema in patients with pre existing cardiac disease
  • Dysrhythmias (VT, VF)
21
Q

ONDANSETRON - Adverse Effects

A
  • Headache and/or flushing
  • Seizures and movement disorders
  • Visual disturbance
  • Hypersensitivity reactions (including anaphylaxis)
22
Q

SALBUTAMOL - Adverse Effects

A
  • Dysrhythmias in large doses
  • Shakes and tremors
23
Q

SODIUM BICARBONATE – adverse effects

A
  • Metabolic alkalosis (may cause dysrhythmias)
  • Hypokalaemia (may cause dysrhythmias)
  • Heart failure
24
Q

KETAMINE - Adverse Effects

A
  • Distressing psychological reactions (e.g. agitation, hallucinations and/or dysphoria)
  • Nausea and Vomiting
  • Muscle effects including increased tone, random purposeless movements

ASNSW ICP STUDY (10 decks)

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