Pharmacology Flashcards
1
Q
What is pharmacology?
A
Study of the ACTION OF DRUGS on the function of living systems
2
Q
What things can drugs target?
A
- Receptors
- Ion Channels
- Enzymes
- Transporters
extras include circulating proteins, DNA, bacterial cell wall etc
3
Q
How do local anaesthetics function?
A
- Binds to the Na+ channel INSIDE THE CELL
- LA prevents Na+ influx
- Prevents depolarisation
- Prevents action potential spreading
- Pain NOT perceived
4
Q
How does local anaesthetic stop Na+ influx?
A
Can block the channel or stabilise in the inactivated conformation