Pharmacology Flashcards

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1
Q

What is pharmacology?

A

Study of the ACTION OF DRUGS on the function of living systems

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2
Q

What things can drugs target?

A
  • Receptors
  • Ion Channels
  • Enzymes
  • Transporters

extras include circulating proteins, DNA, bacterial cell wall etc

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3
Q

How do local anaesthetics function?

A
  • Binds to the Na+ channel INSIDE THE CELL
  • LA prevents Na+ influx
  • Prevents depolarisation
  • Prevents action potential spreading
  • Pain NOT perceived
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4
Q

How does local anaesthetic stop Na+ influx?

A

Can block the channel or stabilise in the inactivated conformation

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